Department of Obstetrics and Gynecology and Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Institution of Clinical Sciences Lund, Center for Reproductive Epidemiology, Tornblad Institute, Lund University, Lund, Sweden.
Acta Obstet Gynecol Scand. 2020 May;99(5):669-678. doi: 10.1111/aogs.13795. Epub 2020 Jan 23.
Obese primiparous women with induction of labor are at high risk for a cesarean section. There are contradictory results regarding time in induced labor in relation to maternal body mass index (BMI). It is important to characterize the course of induced labor to prevent unnecessary cesarean section. We aimed to evaluate whether the duration of labor was associated with maternal BMI in primiparous women with induction of labor.
A national retrospective cohort study, including 15 259 primiparae with a single term pregnancy, admitted for induction of labor from January 2014 to August 2017. Data were obtained from the Swedish Pregnancy Registry. Cox regression analyses were used to illustrate the association between BMI and active labor and between BMI and time from admission until start of active labor.
Duration of active labor was shorter in underweight women and prolonged in women with BMI ≥40 kg/m compared with women in other BMI classes, illustrated by Cox regression graphs (P < .001). The median durations of active labor in underweight women were 6.1 and 7.4 hours in women with BMI ≥40 kg/m . The time from admission until start of active labor increased with maternal BMI, illustrated by Cox regression graphs (P < .001) and the median duration increased from 12.9 hours in underweight women to 22.6 hours in women with BMI ≥40 kg/m . The cesarean section rate in active labor increased significantly with BMI (P < .001) from 7.4% in underweight women to 22.0% in women with BMI ≥40 kg/m . Obese and normal weight women had similar rates of spontaneous vaginal delivery (69.9% in the total study population).
The duration of active labor was associated with maternal BMI for underweight women and women with BMI ≥40 kg/m . Although women with BMI ≥40 kg/m who reached the active phase of labor had the same chance for a spontaneous vaginal delivery as normal weight women, the duration of active labor and the cesarean section rate were increased. The time from admission until start of active labor increased successively with maternal BMI.
肥胖初产妇行引产分娩时行剖宫产的风险较高。关于引产时产妇体重指数(BMI)与产程的关系,目前结果存在矛盾。描述引产的产程特点对于预防不必要的剖宫产很重要。本研究旨在评估初产妇引产时的产程时间是否与产妇 BMI 相关。
这是一项全国性的回顾性队列研究,纳入了 2014 年 1 月至 2017 年 8 月期间因单胎足月妊娠行引产的 15259 例初产妇。数据来自瑞典妊娠登记处。采用 Cox 回归分析阐明 BMI 与活跃期产程及入院至活跃期开始时间的关系。
与其他 BMI 组相比,体重过轻(BMI<18.5)和肥胖(BMI≥40kg/m )的女性活跃期产程更短和更长,Cox 回归图表明了这一点(P<.001)。体重过轻的女性中,BMI≥40kg/m 的女性活跃期产程中位数分别为 6.1 和 7.4 小时。入院至活跃期开始的时间随产妇 BMI 增加而延长,Cox 回归图表明了这一点(P<.001),体重过轻的女性中位时间从 12.9 小时延长至 BMI≥40kg/m 的女性的 22.6 小时。活跃期剖宫产率随 BMI 显著增加(P<.001),从体重过轻女性的 7.4%增加至 BMI≥40kg/m 的女性的 22.0%。肥胖和正常体重的女性阴道分娩率相似(研究人群中的总发生率为 69.9%)。
对于体重过轻和 BMI≥40kg/m 的女性,活跃期产程与产妇 BMI 相关。尽管 BMI≥40kg/m 达到活跃期的女性与正常体重女性的阴道分娩机会相同,但活跃期产程时间和剖宫产率增加。入院至活跃期开始的时间随产妇 BMI 逐渐增加。