Department of Pharmacy Practice, Presbyterian College School of Pharmacy, Clinton, SC, USA.
Medical Science Liaison, Janssen Scientific Affairs, LLC, NJ, USA.
J Pharm Pract. 2021 Oct;34(5):703-709. doi: 10.1177/0897190019896498. Epub 2019 Dec 30.
Antibiotics are commonly prescribed for uncomplicated urinary tract infection (UTI) and acute otitis media (AOM) and may be unnecessary at times. The aim of this study was to evaluate prescribing practices for UTIs and AOM in a rural ambulatory care setting and to identify areas for improvement.
In a single-center, retrospective review conducted at a rural clinic, patients diagnosed with uncomplicated UTI and AOM were included. Patients were identified by (ICD-10) codes, and data were collected for visits between January 1, 2017, and December 31, 2017. The primary outcome was to assess adherence of antimicrobial prescribing to current treatment guidelines.
Of the 76 patients identified, 28 met inclusion criteria. Of the 28 patients, 75% received an agent recommended first line in the treatment guidelines, and 18 of the 21 received a recommended dose. Only 17% of patients were prescribed an appropriate duration of treatment.
Opportunities exist for antimicrobial stewardship interventions for uncomplicated UTIs and AOM. Prescribers are not consistently adhering to guidelines in regard to antibiotic choice, dose, or duration. Additional education and stewardship interventions are crucial considering the increased prevalence of antimicrobial resistance.
抗生素常用于治疗简单的尿路感染 (UTI) 和急性中耳炎 (AOM)，但有时可能不必要。本研究旨在评估农村门诊环境中 UTI 和 AOM 的处方实践，并确定需要改进的领域。
在农村诊所进行的单中心回顾性研究中，纳入了诊断为简单 UTI 和 AOM 的患者。通过 (ICD-10) 代码识别患者，并收集了 2017 年 1 月 1 日至 2017 年 12 月 31 日期间的就诊数据。主要结局是评估抗菌药物处方是否符合当前治疗指南。
在确定的 76 名患者中，有 28 名符合纳入标准。在 28 名患者中，75%的患者接受了治疗指南推荐的一线药物，21 名患者中有 18 名接受了推荐剂量。只有 17%的患者接受了适当的治疗时间。
对于简单的 UTI 和 AOM，存在抗菌药物管理干预的机会。在抗生素选择、剂量或持续时间方面，开处方者并未始终遵循指南。考虑到抗菌药物耐药性的增加，额外的教育和管理干预至关重要。
