Earnst M, Bauknecht K J, Hartmann C A, Herter M, Häring R, Dressler S
Chirurgischen Klinik und Poliklinik im Klinikum Steglitz, Freien Universität.
Zentralbl Chir. 1988;113(17):1105-10.
Cryosurgical treatment was applied to normal liver tissue of 13 clinically intact rats, with a view to investigating effects of freezing temperatures upon normal liver tissue. The animals were sacrificed after different intervals from surgery, and their liver tissue was macroscopically and histologically examined. Major postoperative complications were not observed but for one animal which died of wound healing disorder. The method seems to be suitable also for treatment of liver cell carcinoma or liver metastases.
对13只临床健康的大鼠的正常肝组织进行了冷冻手术治疗,旨在研究冷冻温度对正常肝组织的影响。在手术后的不同时间间隔处死动物,并对其肝组织进行大体和组织学检查。除一只动物死于伤口愈合障碍外,未观察到主要的术后并发症。该方法似乎也适用于肝细胞癌或肝转移瘤的治疗。