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卷烟与水烟吸食与红细胞增多症严重程度之间的关联:一项横断面研究。

Association between cigarette & shisha smoking and the severity of polycythemia: A cross sectional study.

作者信息

AlQahtany Fatmah S, Algahtani Farjah H, Alshebly Mashael M, Madkhaly Fatimah M, Ghandour Mohammed K, Almalki Jawhara H, AlOtaibi Wadha S, Salim Asrar, Mendoza Farrah C

机构信息

Department of Pathology, Hematopathology Unit, College of Medicine, King Saud University, King Saud University Medical City, Riyadh, Saudi Arabia.

Department of Medicine, Division of Oncology/Hematology, College of Medicine, King Saud University, King Saud University Medical City, Riyadh, Saudi Arabia.

出版信息

Saudi J Biol Sci. 2020 Jan;27(1):460-464. doi: 10.1016/j.sjbs.2019.11.009. Epub 2019 Nov 21.

Abstract

Tobacco cigarette smoking is assumed to be a key reason of death all over the world. Smoking had both severe as well long-lasting effects on hematological constraints. As per the data available from World Health Organization, every year nearly 5 million individuals die around the world due to the diseases triggered by smoking. Cigarette smoking is linked with an elevated risk of cardiovascular diseases. To examine the association between shisha or cigarette smoking and the severity of polycythemia, present study is a cross-sectional organized at King Saud University Medical City during the period from October 2017 to April 2018. Participants were patients who have hemoglobin level above 160 g/L on multiple reading in KSUMC between May 2015-February 2018. The sample size (227 patients) was computed on single proportion formula, Data were collected through questionnaires and from medical record of the patients. A pilot study was conducted to evaluate the validity of the questionnaire. A statistical analysis was performed using SPSS 21.0 version. A p-value of ≤ 0.05 considered as statistically significant. Out of 227 study subjects, 86 (37.8%) were smokers, (61.6%) were cigarette smokers while (29%), shisha smokers. Total (9.3%) were smoking both cigarette and Shisha. 29% patients had high normal hemoglobin between the ranges of (160-168 g/L), 17.6% patients had pre-polycythemic hemoglobin between the range of (169-171 g/L) and 53% patients were having polycythemic hemoglobin (>172 g/L). The hemoglobin level in non-smokers was 168.74 g/L, hemoglobin level in cigarette smokers was170.7 g/L, hemoglobin level in shisha smokers was 171.4 g/L while hemoglobin level in those who smokes both cigarette and shisha was 175 g/L. Smoking has adverse effects on hemoglobin. Shisha or cigarette Smoking is associated with increase in the hemoglobin levels and the severity of polycythemia. The findings may help in raising the awareness of tobacco smokers.

摘要

吸烟被认为是全球死亡的一个关键原因。吸烟对血液学指标有严重且持久的影响。根据世界卫生组织提供的数据,全球每年有近500万人死于吸烟引发的疾病。吸烟与心血管疾病风险升高有关。为了研究水烟或香烟吸烟与红细胞增多症严重程度之间的关联,本研究是一项于2017年10月至2018年4月期间在沙特国王大学医学城开展的横断面研究。参与者为2015年5月至2018年2月期间在沙特国王大学医学城多次检测血红蛋白水平高于160 g/L的患者。样本量(227名患者)根据单比例公式计算得出,数据通过问卷和患者病历收集。进行了一项试点研究以评估问卷的有效性。使用SPSS 21.0版本进行统计分析。p值≤0.05被视为具有统计学意义。在227名研究对象中,86名(37.8%)为吸烟者,其中61.6%为吸香烟者,29%为吸水烟者。共有9.3%的人既吸香烟又吸水烟。29%的患者血红蛋白处于高正常范围(160 - 168 g/L),17.6%的患者血红蛋白处于红细胞增多症前期范围(169 - 171 g/L),53%的患者血红蛋白处于红细胞增多症范围(>172 g/L)。非吸烟者的血红蛋白水平为168.74 g/L,吸香烟者的血红蛋白水平为170.7 g/L,吸水烟者的血红蛋白水平为171.4 g/L,既吸香烟又吸水烟者的血红蛋白水平为175 g/L。吸烟对血红蛋白有不良影响。吸水烟或吸香烟与血红蛋白水平升高及红细胞增多症的严重程度相关。这些发现可能有助于提高吸烟者的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc50/6933157/0b4fd21affdc/gr1.jpg

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