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改良单极半髋关节置换术治疗股骨近端转移瘤合并病理性骨折:6例病例系列

Modified Unipolar Hemiarthroplasty for the Treatment of Metastatic Lesions of Proximal Femur with Pathological Fractures: Case Series of Six Patients.

作者信息

Lim C Y, Mat-Hassan S, Awang M, Md-Ariff M F, Hau-Abdullah M A

机构信息

Department of Orthopaedics and Traumatology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.

Department of Orthopaedics, Hospital Raja Perempuan Zainab II, Kota Bharu, Malaysia.

出版信息

Malays Orthop J. 2019 Nov;13(3):21-27. doi: 10.5704/MOJ.1911.004.

DOI:10.5704/MOJ.1911.004
PMID:31890106
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6915321/
Abstract

Proximal femur resection and endoprosthetic reconstruction is the preferred treatment for extensive bony destruction and pathological fractures. Due to the relatively high cost of endoprosthesis, we adopted the modified unipolar hemiarthroplasty (MUH) for reconstruction when the mode of treatment was for palliation. This is a retrospective case study of six patients, who had bone and multi-organs metastases with extensive proximal femur involvement with pathologic fractures who underwent resection and MUH reconstruction during the period 2013 to 2017. All patients were classified as Group B / C based on Scandinavian Sarcoma Group survival scoring, with estimated survival of maximum six months. The basic MUH construct consisted of Austin-Moore prosthesis which was secured to a Küntscher nail using cerclage wire and cemented into the femoral canal. Subsequently, the whole length of the prosthesis which remained outside the canal was coated with cement. The mean age was 61.8 years. The mean survival was 3.9 months, post-operation. There was no implant failure during patients' life span; however, a third of the patients developed infection. Wheel chair ambulation was started immediately post-operation for all patients, and two patients progressed to walking frame ambulation. The total cost of each construct was below US$490 in comparison to long-stem hemiarthroplasty (roughly US$ 1700). Our aim was to alleviate pain, facilitate rehabilitation, ease nursing care and improve quality of life for metastatic bone disease patients until end of life. MUH for the treatment of pathological fracture in proximal femoral metastases is a feasible palliative surgical modality in resource-limited settings.

摘要

股骨近端切除及人工关节置换重建术是广泛骨质破坏和病理性骨折的首选治疗方法。由于人工关节假体成本相对较高,当治疗目的为姑息治疗时,我们采用改良单极半髋关节置换术(MUH)进行重建。这是一项对6例患者的回顾性病例研究,这些患者均有骨和多器官转移,股骨近端广泛受累并伴有病理性骨折,于2013年至2017年期间接受了切除及MUH重建手术。根据斯堪的纳维亚肉瘤组生存评分,所有患者均被归类为B/C组,预计生存期最长为6个月。基本的MUH结构由奥斯汀-摩尔假体组成,该假体通过环扎钢丝固定在一根克氏针上,并使用骨水泥固定在股骨髓腔内。随后,留在髓腔外的假体全长用骨水泥包裹。平均年龄为61.8岁。术后平均生存期为3.9个月。患者生存期内无植入物失败情况;然而,三分之一的患者发生了感染。所有患者术后均立即开始使用轮椅行走,2例患者进展为使用助行架行走。与长柄半髋关节置换术(约1700美元)相比,每个结构的总成本低于490美元。我们的目标是缓解疼痛、促进康复、简化护理并提高转移性骨病患者直至生命终末期的生活质量。在资源有限的情况下,MUH用于治疗股骨近端转移瘤的病理性骨折是一种可行的姑息性手术方式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e700/6915321/d48e62b7c05b/moj-13-021-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e700/6915321/0780620f723d/moj-13-021-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e700/6915321/20fb19088749/moj-13-021-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e700/6915321/fabb6d8cdf58/moj-13-021-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e700/6915321/d48e62b7c05b/moj-13-021-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e700/6915321/0780620f723d/moj-13-021-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e700/6915321/20fb19088749/moj-13-021-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e700/6915321/fabb6d8cdf58/moj-13-021-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e700/6915321/d48e62b7c05b/moj-13-021-f4.jpg

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Injury. 2017 Oct;48 Suppl 3:S48-S54. doi: 10.1016/S0020-1383(17)30658-7.
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Complications After Surgical Management of Proximal Femoral Metastasis: A Retrospective Study of 417 Patients.股骨近端转移瘤手术治疗后的并发症:417例患者的回顾性研究
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