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自体移植物重建术治疗继发性主动脉肠瘘:一项回顾性病例系列研究

reconstruction with autologous graft in the treatment of secondary aortoenteric fistulas: A retrospective case series.

作者信息

Feo Claudio F, Ginesu Giorgio C, Pinna Antonio, Galotti Francesca, Paliogiannis Panagiotis, Fancellu Alessando, Porcu Alberto

机构信息

Department of Medical, Surgical and Experimental Sciences, University of Sassari, 07100, Sassari, Italy.

出版信息

Ann Med Surg (Lond). 2019 Dec 6;49:53-56. doi: 10.1016/j.amsu.2019.11.020. eCollection 2020 Jan.

Abstract

Infections caused by secondary aortoenteric fistulas (SAEF) may be extremely complex and threaten patient's life. We report our surgical approach to SAEF consisting in removal of the infected graft and reconstruction using an autologous venous graft. Seven consecutive patients with SAEF treated with graft removal and reconstruction using an autologous venous graft from 2008 to 2017 were reviewed. Six of seven patients (86%) survived 30-day. In one case a graft thrombosis and acute lower limb ischemia occurred requiring re-operations. All patients received injective antibiotic therapy for 20 days, followed by oral therapy for 3 months. There were no major complications at long-term follow-up. Our results suggest that superficial femoral vein reconstruction of the abdominal aorta for SAEF is effective with an acceptable in-hospital mortality and low rate of major complications. We stress the importance of the deep femoral veins to create the graft because the large saphenous vein is often affected by significant intimal hyperplasia that can cause steno-occlusive complications.

摘要

继发性主动脉肠瘘(SAEF)引起的感染可能极其复杂,并威胁患者生命。我们报告了我们针对SAEF的手术方法,包括切除感染的移植物并使用自体静脉移植物进行重建。回顾了2008年至2017年连续7例接受移植物切除并使用自体静脉移植物重建治疗的SAEF患者。7例患者中有6例(86%)存活30天。1例发生移植物血栓形成和急性下肢缺血,需要再次手术。所有患者接受20天的注射用抗生素治疗,随后口服治疗3个月。长期随访无重大并发症。我们的结果表明,SAEF的腹主动脉股浅静脉重建有效,住院死亡率可接受,重大并发症发生率低。我们强调使用股深静脉构建移植物的重要性,因为大隐静脉常受到严重内膜增生的影响,可导致狭窄闭塞性并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afce/6926104/5dab6788b63e/gr1.jpg

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