Fancellu A, Giuliani G, Feo C F, Scanu A M, Porcu A
Università di Sassari, Istituto di Clinica Chirurgica Generale e Terapia Chirurgica.
Ann Ital Chir. 2004 May-Jun;75(3):373-7.
Primary aortoenteric fistulas (PAEF) are rare entities associated with a high mortality. Although several causes have been reported, their occurrence is usually due to erosion of an abdominal aortic aneurysm into the intestinal tract. The most common sites for the fistula are the third and fourth portions of duodenum. The classical triad of gastrointestinal hemorrhage, abdominal mass and abdominal or back pain, though highly suggestive for PAEF, is uncommon. The typical bleeding pattern associated with PAEF is characteristically intermittent, starting with a brief "herald bleeding" followed eventually by major gastrointestinal hemorrhage, often with fatal outcome. The pre-operative examinations are often not helpful and can lead to delayed diagnosis and surgery. In a patient with risk factors for atherosclerosis and significant upper gastrointestinal bleeding in the absence of an evident source, PAEF should be suspected. A high index of suspicion of this condition allows correct diagnosis and definitive treatment to be carried out. If PAEF is suspected and the patient is unstable the surgeon should be prepared to skip the preoperative investigations in favour of early surgical exploration. Definitive treatment includes primary duodenal repair and aortic aneurismal resection with graft "in situ" replacement. The authors present a successfully treated case and stress the importance of clinical suspicion in order to achieve correct diagnosis and treatment.
原发性主动脉肠瘘(PAEF)是一种罕见的疾病,死亡率很高。尽管已报道了多种病因,但其发生通常是由于腹主动脉瘤侵蚀肠道所致。瘘管最常见的部位是十二指肠第三部和第四部。胃肠道出血、腹部肿块以及腹部或背部疼痛的经典三联征虽然对PAEF具有高度提示性,但并不常见。与PAEF相关的典型出血模式具有间歇性特征,始于短暂的“先兆出血”,最终常导致严重的胃肠道出血,往往造成致命后果。术前检查通常并无帮助,可能导致诊断和手术延迟。对于有动脉粥样硬化危险因素且存在明显上消化道出血但无明确出血源的患者,应怀疑PAEF。对此病保持高度怀疑指数有助于进行正确诊断和确定性治疗。如果怀疑PAEF且患者情况不稳定,外科医生应准备好跳过术前检查,尽早进行手术探查。确定性治疗包括十二指肠一期修复以及主动脉瘤切除并进行移植物“原位”置换。作者展示了一例成功治疗的病例,并强调临床怀疑对于实现正确诊断和治疗的重要性。