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干细胞注入式前交叉韧带重建

Stem Cell-Infused Anterior Cruciate Ligament Reconstruction.

作者信息

Youn Gun Min, Remigio Van Gogh Angelica Marie, Alvarez Alyssa, Shin Yin Sophia Sarang, Chakrabarti Moyukh O, McGahan Patrick J, Chen James L

机构信息

Advanced Orthopaedics and Sports Medicine, San Francisco, California, U.S.A.

出版信息

Arthrosc Tech. 2019 Oct 11;8(11):e1313-e1317. doi: 10.1016/j.eats.2019.07.006. eCollection 2019 Nov.

DOI:10.1016/j.eats.2019.07.006
PMID:31890501
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6926314/
Abstract

Anterior cruciate ligament (ACL) tears are unfortunate but common injuries in the athletic population. The standard of care for ACL tears is a surgical intervention to reconstruct the ACL to restore knee functionality as well as quality of life. In recent years, bone marrow aspirate concentrate (BMAC) has seen increasing use in various orthopaedic settings. This increase can be attributed to the potential beneficial qualities that mesenchymal stem cells, progenitor cells, and growth factors, all of which are present in BMAC, can provide. In this technical note and accompanying video, we describe an anatomic allograft ACL reconstruction infused with BMAC to utilize BMAC's potential benefits.

摘要

前交叉韧带（ACL）撕裂在运动员群体中是不幸但常见的损伤。ACL撕裂的标准治疗方法是通过手术干预重建ACL，以恢复膝关节功能和生活质量。近年来，骨髓抽吸浓缩物（BMAC）在各种骨科手术中的应用越来越广泛。这种增加可归因于BMAC中存在的间充质干细胞、祖细胞和生长因子可能具有的有益特性。在本技术说明及随附视频中，我们描述了一种注入BMAC的解剖学异体ACL重建术，以利用BMAC的潜在益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30f6/6926314/cdc7d354bda1/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30f6/6926314/e99d6c5572f5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30f6/6926314/01364f7b2963/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30f6/6926314/486199cd7d68/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30f6/6926314/bc6411770708/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30f6/6926314/9ada4c8a3db9/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30f6/6926314/cdc7d354bda1/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30f6/6926314/e99d6c5572f5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30f6/6926314/01364f7b2963/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30f6/6926314/486199cd7d68/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30f6/6926314/bc6411770708/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30f6/6926314/9ada4c8a3db9/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30f6/6926314/cdc7d354bda1/gr6.jpg

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本文引用的文献

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Arthrosc Tech. 2018 Oct 22;7(11):e1173-e1176. doi: 10.1016/j.eats.2018.07.016. eCollection 2018 Nov.
2
Allograft tendons are a safe and effective option for revision ACL reconstruction: a clinical review.同种异体肌腱是一种安全有效的前交叉韧带重建翻修选择：临床综述。
Knee Surg Sports Traumatol Arthrosc. 2019 Jun;27(6):1771-1781. doi: 10.1007/s00167-018-5147-4. Epub 2018 Sep 21.
3
Biological treatment of the knee with platelet-rich plasma or bone marrow aspirate concentrates.
用富血小板血浆或骨髓抽吸浓缩物对膝关节进行生物治疗。
Acta Orthop. 2017 Dec;88(6):670-674. doi: 10.1080/17453674.2017.1368899. Epub 2017 Aug 23.
4
Effects of Autogenous Bone Marrow Aspirate Concentrate on Radiographic Integration of Femoral Condylar Osteochondral Allografts.自体骨髓抽吸浓缩物对股骨髁异体骨软骨移植影像学整合的影响。
Am J Sports Med. 2017 Oct;45(12):2797-2803. doi: 10.1177/0363546517715725. Epub 2017 Jul 24.
5
Preoperative Planning for ACL Revision Surgery.前交叉韧带翻修手术的术前规划
Sports Med Arthrosc Rev. 2017 Mar;25(1):19-29. doi: 10.1097/JSA.0000000000000140.
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A Review of Current Graft Options for Anterior Cruciate Ligament Reconstruction.前交叉韧带重建当前移植物选择综述
JBJS Rev. 2015 Nov 10;3(11). doi: 10.2106/JBJS.RVW.O.00009.
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Comparison of patient-reported outcomes among those who chose ACL reconstruction or non-surgical treatment.选择前交叉韧带重建或非手术治疗的患者自我报告结局的比较。
Scand J Med Sci Sports. 2017 May;27(5):535-544. doi: 10.1111/sms.12707. Epub 2016 Jun 23.
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