Faculty of Medicine, University of Porto (FMUP), Portugal.
Center for Health Technology and Services Research (CINTESIS), FMUP, Portugal; Department of Clinical Neurosciences and Mental Health, FMUP, Portugal.
Arch Gerontol Geriatr. 2020 Mar-Apr;87:104000. doi: 10.1016/j.archger.2019.104000. Epub 2019 Dec 17.
The objective of this systematic review was to examine whether pain is a risk factor for suicidal behavior (suicide ideation, suicide attempts or suicide) in older adults.
An extensive search was conducted on the following databases: MEDLINE, ISI Web of Knowledge, Scopus and PsycARTICLES. Search terms used were "pain", "suicid*" and "elderly". Studies that assessed the relation between pain and suicidal behavior among people aged ≥60 years were included. Two reviewers independently screened the abstracts and applied selection criteria in the full-text of all included articles.
Results from 38 original research articles were included and reviewed. Moderate/severe pain increased the risk of suicide ideation from OR = 1.13 (95 %CI = 1.02-1.25) to OR = 2.7 (95 %CI = 1.1-7.0). The influence in suicide attempts ranged between OR = 1.92 (95 %CI 1.17-3.15) and 3.63-fold for extreme pain; and one article reported that the risk of a successful suicide was 4.07-fold higher in pain suffering patients. In most studies, this relation was maintained, even after controlling for other risk factors. Arthritis, back/neck problems and headaches were associated with higher risks of suicidal behavior. Pain was also a stronger predictor for suicide in men (OR = 9.9; 95 %CI = 6.0-16.4) than in women (OR = 3.3; 95 %CI = 1.4-7.7).
Our results suggest the existence of a relationship between pain and suicidal behavior in older adults. This information may be extremely relevant to inform suicide prevention strategies.
本系统评价的目的是检验疼痛是否是老年人自杀行为(自杀意念、自杀未遂或自杀)的风险因素。
我们在以下数据库中进行了广泛的检索:MEDLINE、ISI Web of Knowledge、Scopus 和 PsycARTICLES。使用的检索词是“疼痛”、“自杀”和“老年人”。纳入评估≥60 岁人群中疼痛与自杀行为之间关系的研究。两位评审员独立筛选摘要,并在所有纳入文章的全文中应用选择标准。
纳入并回顾了 38 项原始研究文章的结果。中度/重度疼痛使自杀意念的风险增加,OR=1.13(95%CI=1.02-1.25)至 OR=2.7(95%CI=1.1-7.0)。在自杀未遂方面的影响范围在 OR=1.92(95%CI 1.17-3.15)和极端疼痛的 3.63 倍之间;有一篇文章报告称,疼痛患者成功自杀的风险高 4.07 倍。在大多数研究中,即使控制了其他风险因素,这种关系仍然存在。关节炎、背部/颈部问题和头痛与自杀行为的风险增加相关。疼痛也是男性自杀的更强预测因素(OR=9.9;95%CI=6.0-16.4),而不是女性(OR=3.3;95%CI=1.4-7.7)。
我们的结果表明疼痛与老年人自杀行为之间存在关系。这些信息对于制定自杀预防策略可能非常重要。