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原发性甲状腺癌盆腔转移性骨病手术治疗的功能结局:病例系列

Functional outcome of operative treatment for pelvic metastatic bone disease from primary thyroid cancer: A case series.

作者信息

Prabowo Yogi, Asril Elfikri, Wikanjaya Rio

机构信息

Consultant of Orthopaedic Oncology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

Resident of Orthopaedic Surgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

出版信息

Int J Surg Case Rep. 2020;66:288-297. doi: 10.1016/j.ijscr.2019.11.065. Epub 2019 Dec 10.

Abstract

BACKGROUND

Metastatic bone disease (MBD) is the most common malignancy of bone. It is estimated that 70 % of all malignant bone tumors are due to metastasis. The functional outcome from pelvic MBD surgical management has been rarely described in the literature contrary to that of the long bones.

METHOD

We reported three patients that underwent pelvic resection surgery due to pelvic MBD. All of the primary tumors were thyroid cancer. We measure the functional outcome using SF-36 and MSTS (musculoskeletal tumor society) scores after a one-year follow-up.

RESULT

The SF-36 scoring result was that all of the patients had a remarkable improvement in terms of pain (77.5 %, 100 %, and 100 %). All of the patients also still had proper social functioning (75 %, 100 %, and 100 %) and good emotional well-being (72 %, 92 %, and 88 %). According to the MSTS, the second and third case had an excellent functional outcome; however the first case had poor functional outcome CONCLUSION: Surgery remains the choice of therapy for pelvic MBD that results in alleviation of pain and quality of life improvement.

摘要

背景

转移性骨病(MBD)是最常见的骨恶性肿瘤。据估计,所有恶性骨肿瘤中有70%是由转移引起的。与长骨不同,盆腔MBD手术治疗的功能结果在文献中很少被描述。

方法

我们报告了3例因盆腔MBD接受盆腔切除术的患者。所有原发肿瘤均为甲状腺癌。在随访一年后,我们使用SF-36和肌肉骨骼肿瘤学会(MSTS)评分来衡量功能结果。

结果

SF-36评分结果显示,所有患者在疼痛方面均有显著改善(分别为77.5%、100%和100%)。所有患者仍具备适当的社交功能(分别为75%、100%和100%)以及良好的情绪状态(分别为72%、92%和88%)。根据MSTS评分,第二例和第三例患者功能结果极佳;然而,第一例患者功能结果较差。结论:手术仍然是盆腔MBD的治疗选择,可缓解疼痛并改善生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae99/6938941/19c20ebba58a/gr1.jpg

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