Bonham P E, Currier G F, Orr W C, Othman J, Nanda R S
Department of Orthodontics, University of Oklahoma, College of Dentistry, Oklahoma City.
Am J Orthod Dentofacial Orthop. 1988 Nov;94(5):384-92. doi: 10.1016/0889-5406(88)90127-8.
This study combined the use of cephalometrics and overnight polysomnographic monitoring to analyze the effects of a modified functional appliance on airway, sleep, and respiratory variables in patients with obstructive sleep apnea (OSA). Twelve patients without overt anatomic or pathologic evidence of obstruction were selected on the basis of an initial single night of polysomnographic monitoring, which confirmed the diagnosis of obstructive sleep apnea syndrome. The patients subsequently were fitted with a modified functional appliance designed to securely hold the mandible in an anterior-inferior position. A subsequent overnight polysomnographic study was obtained with each patient wearing the appliance. Lateral cephalometric radiographs with and without the appliance in place were also obtained. The mean vertical and horizontal changes in mandibular position while wearing the appliance were 8.49 mm and 2.28 mm, respectively. The findings indicate that 10 of the 12 patients had decreases in the rate of complete airway obstructions from a mean of 28.86 to 18.69 events per hour, and in the total apnea index from a mean of 53.81 to 35.99 events per hour. A reduction in the rate of obstructive events is attributed to the effect of the appliance on the oropharyngeal structures. Six cephalometric measurements are presented to provide a means of assessing effects of the appliance on the oropharynx and associated structures. The modified functional appliance is a conservative, successful treatment alternative that could benefit patients with obstructive sleep apnea syndrome.
本研究结合使用头影测量法和夜间多导睡眠监测,以分析改良功能性矫治器对阻塞性睡眠呼吸暂停(OSA)患者气道、睡眠和呼吸变量的影响。基于最初一晚的多导睡眠监测结果,选择了12例无明显解剖学或病理学阻塞证据的患者,该监测结果证实了阻塞性睡眠呼吸暂停综合征的诊断。随后,为这些患者佩戴一种改良的功能性矫治器,该矫治器旨在将下颌稳固地保持在前下位置。每位患者佩戴该矫治器时均进行了后续的夜间多导睡眠研究。同时还获取了佩戴矫治器前后的头颅侧位X线片。佩戴矫治器时下颌位置的平均垂直和水平变化分别为8.49毫米和2.28毫米。研究结果表明,12例患者中有10例的完全气道阻塞发生率从平均每小时28.86次降至18.69次,总呼吸暂停指数从平均每小时53.81次降至35.99次。阻塞性事件发生率的降低归因于该矫治器对口咽结构的作用。文中给出了六项头影测量结果,以提供一种评估该矫治器对口咽及相关结构影响的方法。改良功能性矫治器是一种保守且成功的治疗选择,可能会使阻塞性睡眠呼吸暂停综合征患者受益。