两例异基因干细胞移植后出现毛发红糠疹样移植物抗宿主病。
Pityriasis rubra pilaris-like graft-vs-host disease following allogeneic stem cell transplant in two patients.
作者信息
Wang Jennifer Y, Tabata Mika M, Pugliese Silvina, Phillips Darci, Kim Jinah, Weng Wen-Kai, Kwong Bernice Y
机构信息
Department of Dermatology Stanford University Medical Center Stanford California.
Department of Pathology Stanford University Medical Center Stanford California.
出版信息
Clin Case Rep. 2019 Nov 14;7(12):2491-2494. doi: 10.1002/ccr3.2458. eCollection 2019 Dec.
Chronic cutaneous graft-vs-host disease (GVHD) has several atypical variants. We describe two cases of GVHD with clinical and histopathologic features of pityriasis rubra pilaris (PRP), which responded to additional immunosuppression. Recognition of this newly described PRP-like clinical presentation of GVHD may prompt early consideration of additional steroid-sparing therapies.
慢性皮肤移植物抗宿主病（GVHD）有几种非典型变体。我们描述了两例具有毛发红糠疹（PRP）临床和组织病理学特征的GVHD病例，这两例病例对额外的免疫抑制治疗有反应。认识到这种新描述的类似PRP的GVHD临床表现可能会促使早期考虑额外的类固醇节省疗法。
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