Saratov State University, Saratov, Russia.
Saratov State Medical University, Saratov, Russia.
Adv Exp Med Biol. 2020;1232:63-68. doi: 10.1007/978-3-030-34461-0_9.
This seems to be the time to gain new knowledge about the meningeal lymphatic system and a deeper understanding of its anatomy and physiology. Although it is known that the meningeal lymphatics present in the layers of the brain, limited information is available about the role of this system in brain function. Here, for the first time we clearly demonstrate that the meningeal lymphatic pathway is involved in brain clearing from the blood after intracranial hemorrhage associated with hypoxia and forms a connective bridge between interstitial, cerebral spinal fluid and peripheral lymphatics. We also show that the development of methods to stimulate meningeal lymph flow after hemorrhagic evidence in the brain might be a neuroprotective strategy for effective recovery of the brain after a cerebrovascular catastrophe.
这似乎是时候获得有关脑膜淋巴系统的新知识，并更深入地了解其解剖结构和生理学了。尽管已知脑膜淋巴管存在于大脑的各个层中，但有关该系统在大脑功能中的作用的信息有限。在这里，我们首次清楚地表明，脑膜淋巴途径参与了缺氧相关颅内出血后血液从大脑中的清除，并在脑实质、脑脊髓液和外周淋巴之间形成了连接桥梁。我们还表明，开发在脑出血后刺激脑膜淋巴流动的方法可能是一种神经保护策略，有助于在脑血管灾难后大脑的有效恢复。
