Department of Urology, Klinikum Sindelfingen-Böblingen, Sindelfingen, Germany.
Curr Opin Urol. 2020 Mar;30(2):107-112. doi: 10.1097/MOU.0000000000000713.
Miniaturization was the major trend in percutaneous nephrolithotomy in the past 15 years, aiming to lower tract-size-related complication rates while maintaining good stone-free-rates (SFR). Although there is some evidence that 18 Fr Mini-percutaneous lithotomy (PCNL) has comparable efficacy to conventional PCNL and a lower risk of bleeding, it is less clear whether further miniaturization led to an even better safety profile while maintaining good SFR. The present review evaluates the latest results on efficacy, safety, and feasibility of miniaturized techniques 14 Fr or less in PCNL.
Recent literature of the last 2 years reported outcomes of different systems from 4.85 to 14 Fr. Most of these studies demonstrated good efficacy when comparing with RIRS or conventional PCNL. Limitations were a decrease in SFR for stone sizes more than 2 cm, a longer operative time and the likelihood of pathologic intrarenal pressure (IRP) with a higher risk of postoperative fever or sepsis.
Miniaturization of PCNL is an innovative approach in order to lower complication rates and hospitalization time for therapy of renal stones. Limitations like longer OR time or higher IRP may limit the benefit of super miniaturized systems. Currently, the 18 Fr Mini-PCNL seems to be the most reliable solution for stones up to 25 mm, whereas RIRS remains the first choice in renal stones less than 10 mm.
在过去的 15 年中,经皮肾镜取石术的主要趋势是微创化,目的是降低与通道相关的并发症发生率,同时保持良好的结石清除率(SFR)。虽然有证据表明 18Fr 微创经皮肾镜取石术(PCNL)与传统 PCNL 具有相当的疗效,且出血风险较低,但进一步微创化是否能在保持良好 SFR 的同时,带来更安全的效果尚不清楚。本综述评估了最近关于 14Fr 或更小的 PCNL 微创技术的疗效、安全性和可行性的最新结果。
过去 2 年的最新文献报道了 4.85 至 14Fr 不同系统的结果。这些研究大多数都证明了与 RIRS 或传统 PCNL 相比具有良好的疗效。局限性在于对于大于 2cm 的结石,SFR 降低,手术时间延长,以及发生术后发热或败血症的可能性更高的病理性肾内压(IRP)。
PCNL 的微创化是一种创新的方法,旨在降低治疗肾结石的并发症发生率和住院时间。像手术时间延长或更高的 IRP 等限制因素可能会限制超微创系统的益处。目前,18Fr 微创 PCNL 似乎是治疗最大 25mm 结石的最可靠方法,而 RIRS 仍然是治疗小于 10mm 肾结石的首选方法。