儿科糖尿病的变化面貌。
The changing face of paediatric diabetes.
机构信息
University of Cincinnati, Department of Pediatrics, Cincinnati, OH, USA.
Cincinnati Children's Hospital Medical Center, Division of Endocrinology, 3333 Burnet Ave, ML 7012, Cincinnati, OH, 45229, USA.
出版信息
Diabetologia. 2020 Apr;63(4):683-691. doi: 10.1007/s00125-019-05075-6. Epub 2020 Jan 2.
The purpose of this review is to provide an update on the changing face of paediatric type 1 diabetes and type 2 diabetes. Paediatric diabetes is on the rise, with extensive research dedicated to understanding its pathophysiology, comorbidities and complications. As obesity continues to increase among all youth, differentiating between type 1 diabetes and type 2 diabetes has become increasingly difficult but remains important for optimising treatment, anticipating complications and predicting disease risk. Novel treatments are emerging, with the ultimate goal being to achieve glycaemic control, limit weight gain, improve quality of life and reduce comorbidities. In this review, we focus on updates regarding the epidemiology, clinical presentation, comorbidities and complications of paediatric type 1 diabetes and type 2 diabetes and conclude with current and emerging treatments.
本次综述旨在介绍儿童 1 型和 2 型糖尿病的最新变化。儿科糖尿病发病率不断上升，广泛的研究致力于了解其病理生理学、合并症和并发症。随着所有青少年肥胖的持续增加，区分 1 型和 2 型糖尿病变得越来越困难，但对于优化治疗、预测并发症和预测疾病风险仍然很重要。新的治疗方法正在出现，其最终目标是实现血糖控制、限制体重增加、提高生活质量和减少合并症。在本次综述中，我们重点介绍了儿童 1 型和 2 型糖尿病的流行病学、临床表现、合并症和并发症的最新进展，并总结了当前和新兴的治疗方法。
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