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超能文献

Pronounced influence of presystemic metabolism on the metabolic disposition of imrecoxib in renally impaired patients.

作者信息

Srinivas Nuggehally R

机构信息

Department of Innovation and Technology, Jubilant Life Sciences, Sector 59 (D-10), Noida, Uttar Pradesh, India.

Kenox Pharmaceuticals Inc, 11 Deerpark Dr, Suite 128, Princeton Corporate Plaza, Monmouth Junction, NJ, 08852, USA.

出版信息

Eur J Clin Pharmacol. 2020 Mar;76(3):469-471. doi: 10.1007/s00228-019-02824-9. Epub 2020 Jan 3.

DOI:10.1007/s00228-019-02824-9

PMID:31897535

Abstract

摘要

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本文引用的文献

Pharmacokinetic study of imrecoxib in patients with renal insufficiency.

Eur J Clin Pharmacol. 2019 Oct;75(10):1355-1360. doi: 10.1007/s00228-019-02698-x. Epub 2019 Jun 27.

Use of Cocktail Probe Drugs for Indexing Cytochrome P450 Enzymes in Clinical Pharmacology Studies - Review of Case Studies.

Drug Metab Lett. 2019;13(1):3-18. doi: 10.2174/1872312812666181119154734.

Differences in the In Vivo and In Vitro Metabolism of Imrecoxib in Humans: Formation of the Rate-Limiting Aldehyde Intermediate.

Drug Metab Dispos. 2018 Sep;46(9):1320-1328. doi: 10.1124/dmd.118.081182. Epub 2018 Jul 6.

The Role of the Kidney in Drug Elimination: Transport, Metabolism, and the Impact of Kidney Disease on Drug Clearance.

Clin Pharmacol Ther. 2017 Sep;102(3):436-449. doi: 10.1002/cpt.757. Epub 2017 Jul 26.

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Altered disposition of drugs in acute renal failure rat models: drug development strategies and perspectives.

Arzneimittelforschung. 2010;60(12):731-48. doi: 10.1055/s-0031-1296349.

Synthesis and anti-inflammatory activity of the major metabolites of imrecoxib.

Bioorg Med Chem Lett. 2009 Apr 15;19(8):2270-2. doi: 10.1016/j.bmcl.2009.02.090. Epub 2009 Feb 27.

Metabolism and excretion of imrecoxib in rat.

Xenobiotica. 2006 May;36(5):441-55. doi: 10.1080/00498250600595524.

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