Department of Endocrinology and Diabetes and Department of Medical Research, 251 Hellenic Air Force General Hospital, 3 Kanellopoulou Str., 115 25, Goudi, Athens, Greece.
Hellenic Society for the Study of Bone Metabolism, Athens, Greece.
Arch Osteoporos. 2020 Jan 3;15(1):12. doi: 10.1007/s11657-019-0675-1.
We present the second implementation of a fracture liaison service (FLS) at a national level in Greece.
This was a multicenter prospective study, organized by the Hellenic Society for the Study of Bone Metabolism, aiming to investigate the tracking and outcome of patients with low-trauma fractures visiting four university orthopedic departments across the country. The primary endpoint was the participation rate of eligible patients with low-trauma fractures in the program within a time frame of 1 year. Secondary outcomes included the percentage of patients initiating osteoporosis treatment, adherence to treatment, and the percentage of patients experiencing subsequent fractures. A major difference with previous reports was the designed implication of the orthopedic surgeon managing the fracture.
Among the 1350 eligible patients with major osteoporotic fractures, only 396 (29.3%; mean age 78.1 ± 11.6 years; female/male ratio: 4.4) agreed to participate, nearly all of the latter (n = 392) completing the study. With the exception of seven patients, all participants were receiving anti-osteoporotic treatment at the end of the study. Twelve new fractures were recorded at completion of the 12-month follow-up, which were all sustained in patients who either declined to receive anti-osteoporotic treatment or who discontinued treatment despite advice to the contrary.
The participation rate remains low and needs improvement. However, we report herein that whenever the treating physician is involved in the FLS structure, patients are more easily convinced to complete the program, to receive anti-osteoporotic treatment, and to stay connected throughout with the outpatient clinic.
我们在希腊全国范围内实施了第二个骨折联络服务(FLS)。
这是一项多中心前瞻性研究,由希腊骨代谢研究学会组织,旨在调查全国四家大学骨科就诊的低创伤骨折患者的跟踪和结局。主要终点是在 1 年内符合条件的低创伤骨折患者参与该计划的参与率。次要结局包括开始骨质疏松症治疗的患者比例、治疗依从性以及发生后续骨折的患者比例。与之前的报告相比,一个主要的区别是设计了让骨科医生管理骨折。
在 1350 名符合条件的主要骨质疏松性骨折患者中,只有 396 名(29.3%;平均年龄 78.1±11.6 岁;女性/男性比例:4.4)同意参与,其中几乎所有患者(n=392)都完成了研究。除了 7 名患者外,所有参与者在研究结束时都在接受抗骨质疏松治疗。在 12 个月的随访结束时记录到 12 例新骨折,均发生在拒绝接受抗骨质疏松治疗或尽管有建议但仍停止治疗的患者中。
参与率仍然较低,需要提高。然而,我们在此报告,只要治疗医生参与 FLS 结构,患者就更容易被说服完成该计划、接受抗骨质疏松治疗,并在整个过程中与门诊保持联系。