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老年人跌倒后就诊于急诊科的颅内出血发生率:一项系统评价。

Incidence of intracranial bleeding in seniors presenting to the emergency department after a fall: A systematic review.

机构信息

Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

出版信息

Injury. 2020 Feb;51(2):157-163. doi: 10.1016/j.injury.2019.12.036. Epub 2019 Dec 26.

Abstract

INTRODUCTION

Seniors who fall are an increasing proportion of the patients who are treated in emergency departments (ED). Falling on level-ground is the most common cause of traumatic intracranial bleeding. We aimed to determine the incidence of intracranial bleeding among all senior patients who present to ED after a fall.

METHOD

We performed a systematic review. Medline, EMBASE, Cochrane, and Database of Abstracts of Reviews of Effects databases, Google Scholar, bibliographies and conference abstracts were searched for articles relevant to senior ED patients who presented after a ground-level fall. Studies were included if they reported on patients aged 65 or older who had fallen. At least 80% of the population had to have suffered a ground-level fall. There were no language restrictions. We performed a meta-analysis (using the random effects model) to report the pooled incidence of intracranial bleeding within 6 weeks of the fall.

RESULTS

We identified eleven studies (including 11,102 patients) addressing this clinical question. Only three studies were prospective in design. The studies varied in their inclusion criteria, with two requiring evidence of head injury and four requiring the emergency physician to have ordered a head computed tomography (CT). One study excluded patients on therapeutic anticoagulation. Overall, there was a high risk of bias for eight out of eleven studies. The pooled incidence of intracranial bleeding was 5.2% (95% CI 3.2-8.2%). A sensitivity analysis excluding studies with a high risk of bias gave a pooled estimate of 5.1% (95% CI 3.6-7.2%).

CONCLUSION

We found a lack of high-quality evidence on senior ED patients who have fallen. The available literature suggests there is around a 5% incidence of intracranial bleeding in seniors who present to the ED after a fall.

摘要

简介

在急诊科(ED)接受治疗的患者中,老年人跌倒的比例越来越高。平地跌倒是创伤性颅内出血的最常见原因。我们旨在确定所有在 ED 因跌倒而就诊的老年患者中颅内出血的发生率。

方法

我们进行了系统评价。检索了 Medline、EMBASE、Cochrane、Effect 数据库摘要数据库、Google Scholar、参考文献和会议摘要,以获取与 ED 老年患者跌倒后就诊相关的文章。如果研究报告了年龄在 65 岁或以上且跌倒的患者,则将其纳入研究。至少 80%的人群必须发生过平地跌倒。无语言限制。我们进行了荟萃分析(使用随机效应模型),以报告跌倒后 6 周内颅内出血的 pooled 发生率。

结果

我们确定了十一项研究(包括 11102 名患者)来解决这一临床问题。只有三项研究设计为前瞻性。这些研究的纳入标准各不相同,其中两项研究需要有头部受伤的证据,四项研究需要急诊医师已下令进行头部 CT 检查。一项研究排除了正在接受抗凝治疗的患者。总的来说,十一项研究中有八项存在高偏倚风险。颅内出血的 pooled 发生率为 5.2%(95%CI 3.2-8.2%)。排除高偏倚风险研究的敏感性分析得出 pooled 估计值为 5.1%(95%CI 3.6-7.2%)。

结论

我们发现缺乏关于 ED 老年患者跌倒的高质量证据。现有文献表明,在 ED 因跌倒而就诊的老年人中,颅内出血的发生率约为 5%。

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