Nicolas J, Vieillefond A, Benoit G, Jardin A, Neveux Y, Martin E
Centre de Recherches du Service de Santé des Armées, Clamart.
Ann Urol (Paris). 1988;22(4):246-8.
In the context of investigation of a prognostic marker applicable to bladder tumours, the authors propose the cytofluorometric study of the membrane potential of malignant urothelial cells using a molecular probe, 3,3' dihexyloxacarbocyanine. This preliminary study demonstrated a significant increase in the membrane potential of malignant urothelial cells in comparison with normal cells, which leads the authors to propose this cellular parameter as a new tool in the prognostic evaluation of bladder tumours.
在一项适用于膀胱肿瘤的预后标志物研究中，作者提出使用分子探针3,3'-二己基氧杂羰花青对恶性尿路上皮细胞膜电位进行细胞荧光测定研究。这项初步研究表明，与正常细胞相比，恶性尿路上皮细胞的膜电位显著增加，这使得作者提出将这一细胞参数作为膀胱肿瘤预后评估的一种新工具。
