Escola Paulista de Medicina-Universidade Federal de São Paulo, São Paulo, Brazil.
J Surg Oncol. 2020 Apr;121(5):863-872. doi: 10.1002/jso.25821. Epub 2020 Jan 4.
Despite the fact laparoscopic liver resections (LLR) for cholangiocarcinoma is still limited, this systematic review addressed surgical and oncological outcomes of LLR to treat both perihilar cholangiocarcinoma (pCCA) and intrahepatic cholangiocarcinoma (iCCA). Five comparative and 20 noncomparative studies were found. Regarding iCCA, LLR had lower blood loss and less need for Pringle maneuver. However, open liver resections (OLR) were performed more for major hepatectomies, with better lymphadenectomy rates and higher number of harvested lymph nodes. High heterogeneity and selection bias were suggested for iCCA studies.
尽管腹腔镜肝切除术(LLR)治疗胆管癌仍然有限,但本系统评价旨在探讨 LLR 治疗肝门部胆管癌(pCCA)和肝内胆管癌(iCCA)的手术和肿瘤学结果。共发现 5 项对比研究和 20 项非对比研究。对于 iCCA,LLR 术中出血量较少,Pringle 阻断需求较低。然而,对于较大范围的肝切除术,开腹肝切除术(OLR)更为常见,淋巴结清扫率更高,采集的淋巴结数量更多。对于 iCCA 的研究,存在高度异质性和选择偏倚。