von Kuster L C, Genta R M
Department of Pathology and Laboratory Medicine, Veterans Administration Medical Center, University of Cincinnati College of Medicine, OH.
Arch Dermatol. 1988 Dec;124(12):1826-30. doi: 10.1001/archderm.124.12.1826.
Strongyloides stercoralis is a small intestinal nematode that has the ability to multiply within the human host. Because of the potential opportunistic behavior of this parasite, immunocompromised patients may develop fatal disseminated infections. Chronic strongyloidiasis may last decades and give rise to various dermatologic lesions, the most characteristic of which is larva currens, a serpiginous creeping urticarial eruption caused by the intradermal migration of the infective filariform larvae. Rarely recognized is the presence of widespread petechiae and purpura that may develop in patients with disseminated infections. A 64-year-old immunosuppressed man developed fatal extraintestinal S stercoralis infection with extensive purpura associated with massive invasion of the skin by migrating larvae.
粪类圆线虫是一种能够在人类宿主体内繁殖的小肠线虫。由于这种寄生虫具有潜在的机会致病行为，免疫功能低下的患者可能会发生致命的播散性感染。慢性粪类圆线虫病可能持续数十年，并引发各种皮肤病变，其中最具特征性的是匐行疹，这是一种由感染性丝状蚴在真皮内移行引起的蜿蜒状匐行性荨麻疹样皮疹。播散性感染患者中可能出现的广泛瘀点和紫癜很少被认识到。一名64岁的免疫功能低下男性发生了致命的肠外粪类圆线虫感染，伴有广泛紫癜，与幼虫大量侵袭皮肤有关。
