Kram H B, Appel P L, Shoemaker W C
Department of Surgery, King-Drew Medical Center, Los Angeles, CA 90059.
Ann Surg. 1988 Nov;208(5):615-8. doi: 10.1097/00000658-198811000-00012.
A retrospective analysis of all patients with traumatic thoracic aortic rupture (TAR) admitted to the hospital over a consecutive 10-year period was performed in order to define the incidence, morbidity, and mortality of associated cardiac contusion (CC) in patients with TAR. Of the 13 patients with TAR, eight (62%) had associated CC. All patients with CC had two or more of the following positive findings: abnormal ECG, elevated myocardial-band creatinine kinase levels, abnormal radionuclide angiography/left ventricular segmental wall motion studies, or cardiac damage seen at surgery and postmortem examination. Four patients with TAR suffered cardiac arrest; all of the latter patients had associated CC. After successful repair of the TAR, five of six patients with combined TAR and CC developed adult respiratory distress syndrome (ARDS), whereas only one of five patients with isolated TAR had ARDS. All patients with isolated TAR survived, whereas three of eight patients suffering combined TAR and CC died perioperatively, secondary to cardiac arrest. In patients with TAR, the presence of associated CC occurs with increased frequency, is associated with increased morbidity (cardiac arrest, ARDS), and results in increased operative mortality secondary to cardiac instability. A branch-chain decision tree (clinical algorithm) was developed as a means of improving management of patients with combined TAR and CC, including indications for preoperative pulmonary artery catheterization.
为了确定创伤性胸主动脉破裂(TAR)患者中相关心脏挫伤(CC)的发病率、发病率和死亡率,对连续10年入院的所有TAR患者进行了回顾性分析。在13例TAR患者中,8例(62%)伴有CC。所有CC患者均有以下两项或更多阳性结果:心电图异常、心肌带肌酸激酶水平升高、放射性核素血管造影/左心室节段壁运动研究异常,或手术及尸检时可见心脏损伤。4例TAR患者发生心脏骤停;所有这些患者均伴有CC。TAR成功修复后,6例合并TAR和CC的患者中有5例发生成人呼吸窘迫综合征(ARDS),而5例单纯TAR患者中只有1例发生ARDS。所有单纯TAR患者均存活,而8例合并TAR和CC的患者中有3例在围手术期死亡,继发于心脏骤停。在TAR患者中,相关CC的存在频率增加,与发病率增加(心脏骤停、ARDS)相关,并导致因心脏不稳定而增加手术死亡率。开发了一种分支链决策树(临床算法),作为改善合并TAR和CC患者管理的一种手段,包括术前肺动脉导管插入术的指征。