Department of Radiology, University of California San Diego, San Diego, CA, USA.
Diagn Interv Radiol. 2020 Jan;26(1):58-60. doi: 10.5152/dir.2019.19317.
Surgical application of fibrin sealant is well established as a hemostatic agent. However, reports of its percutaneous application and its uses within the urinary tract are limited. Presented below are two patients with recalcitrant urinomas despite diversion therapy following partial nephrectomy for oncocytomas. Both patients were successfully treated with percutaneous application of fibrin sealant via a sheath at the time of percutaneous perinephric drain removal. Follow-up imaging demonstrated resolution of the urinomas with stabilization of creatinine. Percutaneous application of fibrin sealant may be considered as an alternative treatment for recalcitrant urinomas prior to surgical intervention, though more studies are required to confirm its effectiveness and safety.
纤维蛋白粘合剂在外科中作为止血剂已有广泛应用。然而，其经皮应用以及在泌尿道中的用途的报告有限。本文介绍了 2 例肾部分切除术后因肾细胞癌而行引流治疗后仍有顽固肾周脓肿的患者。这 2 例患者均在经皮肾周引流管拔除时通过鞘管进行纤维蛋白粘合剂的经皮应用，治疗后获得成功。随访影像学显示肾周脓肿消退，血肌酐稳定。在手术干预之前，纤维蛋白粘合剂的经皮应用可被视为治疗顽固肾周脓肿的一种替代方法，但还需要更多的研究来证实其疗效和安全性。
