Sarkisov D S, Pal'tsyn A A, Chervonskaia N V, Badikova A K, Ustinova T S
Arkh Patol. 1988;50(7):17-23.
Donors' neutrophils are capable for inhibiting the growth of and killing staphylococci both intra- and extracellularly. In the absence of serum the rate of extracellular killing of microbes by donors' neutrophils is reaching that of killing phagocytized bacteria, while in the serum introduction the rate of intracellular killing overwhelms that of extracellular. Burnt patients' neutrophils fail to control the microbes multiplication either intra- or extracellularly without serum, while in combination with it both intra- and extracellular killing activity of neutrophils of the burnt sharply increases being superior to relevant combination of healthy subjects.
供体的中性粒细胞能够在细胞内和细胞外抑制葡萄球菌的生长并将其杀死。在无血清情况下,供体中性粒细胞对微生物的细胞外杀伤速率达到对吞噬细菌的杀伤速率,而在加入血清后,细胞内杀伤速率超过细胞外杀伤速率。烧伤患者的中性粒细胞在无血清时无法在细胞内或细胞外控制微生物的繁殖,而在与血清结合时,烧伤患者中性粒细胞的细胞内和细胞外杀伤活性均急剧增加,优于健康受试者的相应组合。