Poledníková Karolína, Toušek Petr
Vnitr Lek. 2019 Winter;65(10):659-662.
Takotsubo syndrome (TTS) is currently regarded as a special type of acute coronary syndrome. The syndrome can be trigerred by emotional stress factors and more often by some severe non-cardiac conditions. The long-term outcome of TTS patients is similar to those with myocardial infarction. The exact pathophysiological mechanism is not yet fully explained. Excessive amount of catecholamines released into bloodstream after stress attack plays a crucial role. The transient left ventricle dysfunction is probably caused by combination of several pathophysiological mechanism. There is little data concerning the treatment of TTS. It is important to focus on therapeutic strategies in order to eliminate risk of heart failure or TTS recurrence. The aim of the present review is to bring last known information about this disease.
应激性心肌病(TTS)目前被视为一种特殊类型的急性冠状动脉综合征。该综合征可由情绪应激因素引发,更常见的是由一些严重的非心脏疾病引发。TTS患者的长期预后与心肌梗死患者相似。确切的病理生理机制尚未完全阐明。应激发作后释放到血液中的儿茶胺过量起关键作用。短暂性左心室功能障碍可能是由多种病理生理机制共同作用引起的。关于TTS治疗的数据很少。关注治疗策略以消除心力衰竭或TTS复发的风险很重要。本综述的目的是提供有关该疾病的最新已知信息。