Schweiger Victor, Cammann Victoria L, Templin Christian
Dtsch Med Wochenschr. 2022 Nov;147(23):1530-1537. doi: 10.1055/a-1810-9242. Epub 2022 Nov 16.
TTS is an acute heart failure syndrome that usually affects postmenopausal women. The Syndrome is often preceded by an emotional or physical trigger. TTS strongly resembles acute myocardial infarction from a clinical standpoint and also exhibits ECG changes in the same proportion. There are specific patterns of wall motion abnormalities, based on which, the syndrome can be divided into four types. Neurological and/or psychiatric comorbidities are common in TTS patients. Therapy is based on the hemodynamic state and the presence of left ventricular outflow tract obstruction or cardiogenic shock. TTS has a comparable mortality to acute myocardial infarction. Pathophysiologically, the activation of the brain-heart axis with acute catecholamine storm seems to inherit a central role.
应激性心肌病是一种急性心力衰竭综合征，通常影响绝经后女性。该综合征常由情绪或身体触发因素诱发。从临床角度来看，应激性心肌病与急性心肌梗死极为相似，且心电图改变的比例相同。存在特定的室壁运动异常模式，据此可将该综合征分为四种类型。应激性心肌病患者常伴有神经和/或精神合并症。治疗基于血流动力学状态以及左心室流出道梗阻或心源性休克的存在情况。应激性心肌病的死亡率与急性心肌梗死相当。在病理生理学上，急性儿茶酚胺风暴导致的脑-心轴激活似乎起着核心作用。
