Lanzara V, Cervellati F, Grazi E
Istituto di Chimica Biologica, Università di Ferrara, Italy.
Biochem Int. 1988 Aug;17(2):217-23.
Xanthine oxidase increases the rate of actin polymerization. This occurs at oxidase concentrations as low as 40 nM provided the concentration of the polymerizing agent is low (0.5 mM MgCl2). In the presence of 0.1 M KCl plus 1 mM MgCl2 as the polymerizing agents, xanthine oxidase does not affect the rate of the polymerization but increases significantly the rate of the conversion of F(ATP)actin into F(ADP.Pi)actin and probably also the rate of the orthophosphate release.
黄嘌呤氧化酶可提高肌动蛋白聚合的速率。只要聚合剂浓度较低（0.5 mM 氯化镁），在低至40 nM 的氧化酶浓度下就会发生这种情况。在存在0.1 M 氯化钾加1 mM 氯化镁作为聚合剂的情况下，黄嘌呤氧化酶不影响聚合速率，但会显著提高F(ATP)肌动蛋白转化为F(ADP.Pi)肌动蛋白的速率，并且可能还会提高正磷酸盐释放的速率。
