Ugai K, Kurosaka M, Hirohata K
Department of Orthopedic Surgery, Kobe University School of Medicine, Japan.
Arthritis Rheum. 1988 Nov;31(11):1442-6. doi: 10.1002/art.1780311116.
We describe 2 patients with pigmented villonodular synovitis. In both patients, synovial fluids (SF) were characterized by the presence of abundant, strongly birefringent lipid microspherules, which appeared as Maltese crosses and were found both inside foam cells and free in the SF. Histologically, the synovial membranes showed pigmented villonodular synovitis, with aggregation of foam cells containing abundant lipid microspherules in their cytoplasm. Observation of numerous birefringent lipid microspherules and foam cells in SF may be a clue to the diagnosis of pigmented villonodular synovitis.
我们描述了2例色素沉着绒毛结节性滑膜炎患者。在这2例患者中，滑液（SF）的特征是存在大量强双折射脂质微球，这些微球呈马耳他十字形，见于泡沫细胞内及游离于滑液中。组织学上，滑膜显示为色素沉着绒毛结节性滑膜炎，泡沫细胞聚集，其细胞质内含有大量脂质微球。在滑液中观察到大量双折射脂质微球和泡沫细胞可能是色素沉着绒毛结节性滑膜炎诊断的线索。
