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社会剥夺对经导管主动脉瓣植入术(TAVI)后结局的影响。

Impact of social deprivation on outcome following transcatheter aortic valve implantation (TAVI).

机构信息

Department of Cardiology, Morriston Hospital, Swansea Bay University Health Board, Swansea, UK.

Systems Immunity University Research Institute, Cardiff University, Cardiff, South Glamorgan, UK.

出版信息

Open Heart. 2019 Dec 5;6(2):e001089. doi: 10.1136/openhrt-2019-001089. eCollection 2019.

Abstract

OBJECTIVES

We sought to evaluate whether socioeconomic status influences outcome after first-time transcatheter aortic valve implantation (TAVI).

METHOD

This is a single-centre study carried out in Swansea, South West Wales, UK between 5 November 2009 and 10 June 2018. Data included age, gender, domiciliary postal code, comorbidities, complications post-TAVI, length of stay, follow-up time and survival status. The Welsh Index of Multiple Deprivation, 2014 was used to stratify cases by level of social deprivation according to domiciliary postal codes.

RESULTS

Study population was 387 patients of whom 213 (54.8%) were men with mean age ±SD of 82.8±8.3 years. Patients, who were less deprived (296 (76.4%)), were more likely to be older (83.5±7.9 vs 80.4±9.3, p<0.05) and to be married (83.2% vs 69.7%, p<0.05). Conversely, 'more deprived' patients (91 (23.6%)) were more likely to have a longer stay in hospital as compared with patients in the 'less deprived group' (29.6±32.7 days vs 21.3±21.1 days, p<0.05). However, 30-day, 1-year and 3-year survival/mortality rates were similar across all socioeconomic levels.

CONCLUSIONS

This is the first study in which social deprivation has been investigated as a risk factor for mortality in a high-risk group of patients with severe aortic stenosis undergoing TAVI. Residing in a 'more deprived' area in South West Wales is not associated with adverse outcome following TAVI but patients who are 'more deprived' tend to stay longer in hospital compared with patients who are 'less deprived'.

摘要

目的

我们旨在评估社会经济地位是否会影响首次经导管主动脉瓣置换术(TAVI)后的结果。

方法

这是一项在英国威尔士斯旺西进行的单中心研究,时间为 2009 年 11 月 5 日至 2018 年 6 月 10 日。数据包括年龄、性别、家庭邮政编码、合并症、TAVI 后并发症、住院时间、随访时间和生存状况。使用 2014 年威尔士多维贫困指数根据家庭邮政编码对病例进行社会剥夺程度分层。

结果

研究人群为 387 例患者,其中 213 例(54.8%)为男性,平均年龄±标准差为 82.8±8.3 岁。社会经济地位较低的患者(296 例(76.4%))年龄更大(83.5±7.9 岁比 80.4±9.3 岁,p<0.05)且已婚(83.2%比 69.7%,p<0.05)的可能性更大。相反,与“较不贫困”组相比,“较贫困”组(91 例(23.6%))的住院时间更长(29.6±32.7 天比 21.3±21.1 天,p<0.05)。然而,所有社会经济水平的 30 天、1 年和 3 年生存率/死亡率相似。

结论

这是第一项研究,其中社会贫困被调查为严重主动脉瓣狭窄患者接受 TAVI 后死亡率的危险因素。居住在南威尔士的“较贫困”地区与 TAVI 后不良结局无关,但与“较不贫困”的患者相比,“较贫困”的患者往往住院时间更长。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e324/6927509/bf9758b07329/openhrt-2019-001089f01.jpg

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