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1994 - 2008年英国冠心病过早死亡的社会不平等趋势:一项时间趋势生态研究

Trends in social inequalities for premature coronary heart disease mortality in Great Britain, 1994-2008: a time trend ecological study.

作者信息

McCartney David, Scarborough Peter, Webster Premila, Rayner Mike

机构信息

Department of Public Health, University of Oxford, Oxford, UK.

出版信息

BMJ Open. 2012 Jun 18;2(3). doi: 10.1136/bmjopen-2011-000737. Print 2012.

Abstract

OBJECTIVE

To compare trends in metrics of socioeconomic inequalities in premature coronary heart disease (CHD) mortality in Great Britain.

DESIGN

Time trend ecological study with area-level deprivation as exposure.

SETTING

Great Britain, 1994-2008.

PARTICIPANTS

Men and women aged younger than 75 years. No lower age limit.

INTERVENTIONS

None.

MAIN OUTCOME MEASURES

CHD mortality rates.

RESULTS

There has been a decrease in socioeconomic inequalities in CHD mortality in absolute terms but an increase in relative terms. CHD mortality rates in men aged younger than 75 years fell by 69 per 100 000 (95% CIs 64 to 74) in the least deprived quintile and by 92 per 100 000 (95% CI 86 to 98) in the most deprived quintile (p for trend: <0.001). Mortality rate ratios comparing the most deprived quintile to the least deprived quintile increased in women aged younger than 75 years from 1.77 (95% CI 1.68 to 1.86) to 2.32 (95% CI 2.14 to 2.52). There was a weak negative association between the average decline of relative rates and area deprivation.

CONCLUSIONS

It could either be said that inequalities in premature mortality from CHD between affluent and deprived areas have widened or narrowed between 1994 and 2008 depending on the measurement technique. In the context of falling CHD mortality rates, narrowing of absolute inequalities is to be expected, but increases in relative inequalities are a cause for concern.

摘要

目的

比较英国早发性冠心病(CHD)死亡率的社会经济不平等指标的趋势。

设计

以地区层面的贫困程度为暴露因素的时间趋势生态学研究。

背景

英国,1994 - 2008年。

参与者

年龄小于75岁的男性和女性。无年龄下限。

干预措施

无。

主要观察指标

冠心病死亡率。

结果

冠心病死亡率的社会经济不平等在绝对意义上有所下降,但在相对意义上有所增加。在最不贫困的五分之一人群中,年龄小于75岁男性的冠心病死亡率每10万人下降了69例(95%可信区间为64至74),而在最贫困的五分之一人群中每10万人下降了92例(95%可信区间为86至98)(趋势p值:<0.001)。在年龄小于75岁的女性中,最贫困五分之一人群与最不贫困五分之一人群的死亡率比值从1.77(95%可信区间为

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3fa/3378944/cdb9b64d4f1a/bmjopen-2011-000737fig1.jpg

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