Larsson H B, Thomsen C, Frederiksen J, Henriksen O, Olesen J
Department of Magnetic Resonance, Hvidovre Hospital, Denmark.
Acta Radiol. 1988 Nov-Dec;29(6):629-32.
Optic neuritis is often the first manifestation of multiple sclerosis (MS). Sixteen patients with acute optic neuritis and one patient with benign intracranial hypertension (BIH) were investigated by magnetic resonance imaging, using a chemical shift selective double spin echo sequence. In 3 of the 16 patients, abnormalities were seen. In one patient with bilateral symptoms, signal hyperintensity and swelling of the right side of the chiasm were found. In another patient the optic nerve was found diffusely enlarged with only a marginally increased signal in the second echo. In the third patient an area of signal hyperintensity and swelling was seen in the left optic nerve. In the patient with BIH the subarachnoid space which surrounds the optic nerves was enlarged. Even using this refined pulse sequence, avoiding the major artefact in imaging the optic nerve, the chemical shift artefact, lesions were only shown in 3/16 (19%) of the patients with optic neuritis. Nevertheless, the presented chemical shift selective double spin echo sequence may be of great value for detection of retrobulbar lesions.
视神经炎通常是多发性硬化症（MS）的首发表现。采用化学位移选择性双自旋回波序列，对16例急性视神经炎患者和1例良性颅内高压（BIH）患者进行了磁共振成像检查。16例患者中有3例出现异常。1例双侧有症状的患者，发现视交叉右侧信号增强和肿胀。另1例患者视神经弥漫性增粗，第二回波中信号仅略有增加。第3例患者左侧视神经可见信号增强和肿胀区域。BIH患者视神经周围的蛛网膜下腔增宽。即使使用这种优化的脉冲序列，避免了视神经成像中的主要伪影即化学位移伪影，视神经炎患者中也仅有3/16（19%）显示有病变。尽管如此，所呈现的化学位移选择性双自旋回波序列对于检测球后视神经病变可能具有重要价值。
