Keio University, Yokohama, Graduate School of Medicine, Kyoto University, Kyoto, and Japan Society for the Promotion of Science, Tokyo, Japan.
Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Arthritis Care Res (Hoboken). 2021 Mar;73(3):328-335. doi: 10.1002/acr.24136.
OBJECTIVE: Knee osteoarthritis (OA) has been suggested to increase the risk of falls. Low back pain (LBP) is a potential risk factor for falls in people with knee OA, but this issue has not been addressed adequately in previous studies. The objective of this study was to investigate the relationship between LBP and falls in people with knee OA in a 12-month period. METHODS: Participants with knee OA (Kellgren/Lawrence [K/L] grade ≥1) completed questionnaires for LBP and falls that occurred in the preceding 12 months. Binary and ordinal logistic regression analyses were performed to assess the relationship between LBP or moderate-to-severe LBP (numeric rating scale ≥4 points) and any fall (≥1 fall) or recurrent falls (≥2 falls) after adjustment for age, sex, K/L grade, knee pain severity, and quadriceps strength. Sensitivity analyses were performed excluding people with sciatica, nonchronic LBP, K/L grade 1, and those receiving pain medications. RESULTS: We included 189 participants (ages 61-90 years, 78.3% women) in this study. Of these participants, 41 (21.6%) reported falls in the preceding 12 months. People with any LBP (n = 101) and those with moderate-to-severe LBP (n = 45) had 2.7- and 3.7-times higher odds of recurrent falls, respectively. Sensitivity analyses revealed a strong correlation between moderate-to-severe LBP and recurrent falls. CONCLUSION: Thorough investigation of LBP as a risk factor for recurrent falls in people with knee OA may provide a novel insight into the pathomechanics of recurrent falls in this population.
目的:膝骨关节炎(OA)已被认为会增加跌倒的风险。下腰痛(LBP)是膝 OA 患者跌倒的潜在危险因素,但之前的研究并未充分解决这一问题。本研究旨在探讨 12 个月内膝 OA 患者的 LBP 与跌倒之间的关系。
方法:患有膝 OA(Kellgren/Lawrence [K/L] 分级≥1)的参与者完成了关于 LBP 和过去 12 个月内发生的跌倒的问卷。进行了二元和有序逻辑回归分析,以评估 LBP 或中度至重度 LBP(数字评分量表≥4 分)与任何跌倒(≥1 次跌倒)或复发性跌倒(≥2 次跌倒)之间的关系,调整了年龄、性别、K/L 分级、膝关节疼痛严重程度和股四头肌力量。进行了敏感性分析,排除了坐骨神经痛、非慢性 LBP、K/L 分级 1 和接受止痛药物治疗的患者。
结果:本研究纳入了 189 名参与者(年龄 61-90 岁,78.3%为女性)。其中,41 人(21.6%)在过去 12 个月内发生过跌倒。有任何 LBP(n=101)和中度至重度 LBP(n=45)的患者发生复发性跌倒的几率分别为 2.7 倍和 3.7 倍。敏感性分析显示,中度至重度 LBP 与复发性跌倒之间存在很强的相关性。
结论:深入研究 LBP 作为膝 OA 患者复发性跌倒的危险因素,可能为该人群复发性跌倒的发病机制提供新的见解。
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