Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Department of Visceral Surgery, Lausanne University Hospital, Lausanne, Switzerland.
Br J Surg. 2020 Apr;107(5):546-551. doi: 10.1002/bjs.11399. Epub 2020 Jan 7.
This study aimed to identify patients eligible for a 48-h stay after colorectal resection, to provide guidance for early discharge planning.
A bi-institutional retrospective cohort study was undertaken of consecutive patients undergoing major elective colorectal resection for benign or malignant pathology within a comprehensive enhanced recovery pathway between 2011 and 2017. Overall and severe (Clavien-Dindo grade IIIb or above) postoperative complication and readmission rates were compared between patients who were discharged within 48 h and those who had hospital stay of 48 h or more. Multinominal logistic regression analysis was performed to ascertain significant factors associated with a short hospital stay (less than 48 h).
In total, 686 of 5122 patients (13·4 per cent) were discharged within 48 h. Independent factors favouring a short hospital stay were age below 60 years (odds ratio (OR) 1·34; P = 0·002), ASA grade less than III (OR 1·42; P = 0·003), restrictive fluid management (less than 3000 ml on day of surgery: OR 1·46; P < 0·001), duration of surgery less than 180 min (OR 1·89; P < 0·001), minimally invasive approach (OR 1·92; P < 0·001) and wound contamination grade below III (OR 4·50; P < 0·001), whereas cancer diagnosis (OR 0·55; P < 0·001) and malnutrition (BMI below 18 kg/m : OR 0·42; P = 0·008) decreased the likelihood of early discharge. Patients with a 48-h stay had fewer overall (10·8 per cent versus 30·6 per cent in those with a longer stay; P < 0·001) and fewer severe (2·6 versus 10·2 per cent respectively; P < 0·001) complications, and a lower readmission rate (9·0 versus 11·8 per cent; P = 0·035).
Early discharge of selected patients is safe and does not increase postoperative morbidity or readmission rates. In these patients, outpatient colorectal surgery should be feasible on a large scale with logistical optimization.
本研究旨在确定结直肠切除术后适合 48 小时住院的患者,为早期出院计划提供指导。
本研究采用回顾性、双机构队列研究方法,纳入 2011 年至 2017 年间在全面强化康复途径下接受择期主要结直肠切除术的良性或恶性病理患者。比较 48 小时内出院患者和住院时间超过 48 小时患者的总并发症和严重(Clavien-Dindo 分级 IIIb 或以上)并发症和再入院率。采用多项逻辑回归分析确定与短期住院(少于 48 小时)相关的显著因素。
共 5122 例患者中有 686 例(13.4%)在 48 小时内出院。有利于短期住院的独立因素包括年龄<60 岁(优势比[OR]1.34;P=0.002)、ASA 分级<III 级(OR 1.42;P=0.003)、限制液体管理(手术当天<3000ml:OR 1.46;P<0.001)、手术时间<180min(OR 1.89;P<0.001)、微创方法(OR 1.92;P<0.001)和伤口污染分级<III 级(OR 4.50;P<0.001),而癌症诊断(OR 0.55;P<0.001)和营养不良(BMI<18kg/m :OR 0.42;P=0.008)降低了早期出院的可能性。48 小时住院患者的总并发症发生率(10.8%比住院时间较长患者的 30.6%;P<0.001)和严重并发症发生率(2.6%比 10.2%;P<0.001)均较低,再入院率也较低(9.0%比 11.8%;P=0.035)。
选择合适的患者进行早期出院是安全的,不会增加术后发病率或再入院率。在这些患者中,具有后勤优化的门诊结直肠手术应该是可行的。