Center for Supramolecular Chemistry & Catalysis and Department of Chemistry, College of Science , Shanghai University , 99 Shang-Da Road , Shanghai 200444 , P. R. China.
Department of Physics, College of Science , Shanghai University , 99 Shang-Da Road , Shanghai 200444 , P. R. China.
J Am Chem Soc. 2020 Feb 5;142(5):2396-2403. doi: 10.1021/jacs.9b11595. Epub 2020 Jan 27.
Radical reduction of alkyl halides and aerobic oxidation of alkyl aromatics are reported using water-soluble container compounds ( and ). The reductions involve α,ω-dihalides (- and ) with radical initiators in cavitand hosts with varied binding affinities. Product distributions lead to general guidelines for the use of dynamic supramolecular systems with fast reactions. The binding of guest substrates in the hosts must show high affinities ( > 10 M) to ensure that the reactions take place under confinement in the containers.
使用水溶性容器化合物（和），我们报道了卤代烷烃的自由基还原和烷基芳烃的有氧氧化。这些还原反应涉及α，ω-二卤代物（-和），在具有不同结合亲和力的穴状配体主体中使用自由基引发剂。产物分布为使用具有快速反应的动态超分子体系提供了一般指南。客体底物在主体中的结合必须具有高亲和力（> 10 M），以确保反应在容器的限制内进行。
