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首次急性风湿热发作后儿童中期随访中瓣膜反流的变化:更新后的琼斯标准后的首次评估。

Changes in valvular regurgitation in mid-term follow-up of children with first attack acute rheumatic fever: first evaluation after the updated Jones criteria.

机构信息

Department of Pediatric Cardiology, Ataturk University Medical Faculty, Erzurum, Turkey.

出版信息

Cardiol Young. 2020 Mar;30(3):369-371. doi: 10.1017/S1047951119003317. Epub 2020 Jan 10.

DOI:10.1017/S1047951119003317
PMID:31920190
Abstract

AIM

In present study, we aimed to evaluate the changes in valvular regurgitations in mid-term follow-up of children with first attack acute rheumatic fever diagnosed after updated Jones criteria.

MATERIALS AND METHODS

The medical records of the children diagnosed with acute rheumatic fever between June 2015 and November 2018 were evaluated retrospectively. When compared to the findings during diagnosis, the changes in the degree of valvular regurgitation in the last visit were coded as same, regressed, or disappeared.

RESULTS

A total of 50 children were diagnosed with the first attack of acute rheumatic fever between the noted dates. Nine patients (18%) could be diagnosed depending on the new criteria. Eight patients did not have carditis, and 35 patients (49 valves) could be followed for a median follow-up period of 11.7 ± 3.3 months. In our study, the valvar lesions continued in 82% of patients with clinical carditis at the end of the first year and the degree of valvular regurgitation decreased in 39% of them. Despite this, in a significantly higher (p = 0.031) ratio of patients with silent carditis (41%), valvar lesions disappeared in the same follow-up period. In 18.4% of the involved valves, regurgitation regressed to physiological level.

CONCLUSION

Updated Jones criteria make it possible to diagnose a significant number of patients, and the ratio of complete recovery among patients with silent carditis is significantly higher. Also, it can be speculated that the normal children in whom a physiological mitral regurgitation is detected should be followed in terms of rheumatic heart disease.

摘要

目的

本研究旨在评估根据更新后的琼斯标准诊断的首次发作急性风湿热患儿中期随访时瓣膜反流的变化。

材料与方法

回顾性分析 2015 年 6 月至 2018 年 11 月诊断为急性风湿热的患儿的病历。与诊断时的发现相比,最后一次就诊时瓣膜反流程度的变化编码为相同、消退或消失。

结果

共有 50 例患儿在上述日期内被诊断为首次发作急性风湿热。根据新标准,有 9 例(18%)可确诊。8 例患儿无心脏炎,35 例患儿(49 个瓣)可随访,中位随访时间为 11.7±3.3 个月。在本研究中,临床心脏炎患儿在第一年结束时瓣膜病变持续存在,82%;其中 39%的反流程度减轻。尽管如此,在无症状性心脏炎(41%)患者中,瓣膜病变在同一随访期消失的比例明显更高(p=0.031)。在 18.4%受累瓣中,反流消退至生理水平。

结论

更新后的琼斯标准可诊断出大量患者,无症状性心脏炎患者完全恢复的比例明显更高。此外,可以推测,在检测到生理性二尖瓣反流的正常儿童中,应针对风湿性心脏病进行随访。

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