Melanocytic Skin Tumors: Does the Molecular Progression Model Fit With the Routine Clinicopathological Practice?
作者信息
Ferrara Gerardo, Bradamante Mirna
机构信息
Anatomic Pathology Unit, Macerata General Hospital, Macerata, Italy.
Department of Dermatology and Venereology, University Hospital Centre Zagreb, Croatia.
出版信息
Dermatol Pract Concept. 2019 Dec 31;10(1):e2020001. doi: 10.5826/dpc.1001a01. eCollection 2020.
Abstract
摘要
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Virchows Arch. 2019 May;474(5):539-550. doi: 10.1007/s00428-019-02533-9. Epub 2019 Feb 12.
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An update on molecular alterations in melanocytic tumors with emphasis on Spitzoid lesions.黑素细胞肿瘤分子改变的最新进展，重点关注Spitz样病变。
Ann Transl Med. 2018 Jun;6(12):249. doi: 10.21037/atm.2018.05.23.
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Combined activation of MAP kinase pathway and β-catenin signaling cause deep penetrating nevi.丝裂原活化蛋白激酶（MAP）途径和β-连环蛋白信号的联合激活导致深部浸润性痣。
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Atypical Spitz tumours and sentinel lymph node biopsy: a systematic review.非典型 Spitz 肿瘤与前哨淋巴结活检：系统评价。
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A distinct subset of atypical Spitz tumors is characterized by BRAF mutation and loss of BAP1 expression.一类具有独特特征的非典型 Spitz 肿瘤，其特征为 BRAF 突变和 BAP1 表达缺失。
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