Girişgen İlknur, Yüksel Selçuk, Karcılı Kadriye, Becerir Tülay
Department of Pediatric Nephrology, Pamukkale University School of Medicine, Denizli, Turkey.
Department of Pediatric Nephrology-Rheumatology, Pamukkale University School of Medicine, Denizli, Turkey.
Turk J Urol. 2020 Jan 6;46(2):152-158. doi: 10.5152/tud.2019.19170. Print 2020 Mar.
Pediatric urolithiasis is a globally growing problem. The composition and frequency of urinary tract stones vary not only among different countries, but across various regions in a country. Hence, we aimed to identify the types and frequencies of urinary tract stones in children from our region (Inner Western Anatolian part of Turkey), and to compare our findings with the results from other regions in our country.
In this retrospective analysis of 53 pediatric urolithiasis cases that were treated in our hospital between 2009 and 2019, the demographic data, clinical course, radiological and metabolic findings, the recurrence rate, and the composition of the stones were evaluated.
The mean age of the patients was 5.9±4.6 (0.5-18) years, and there were 30 (56.6%) girls and 23 (43.4%) boys. An analysis of the composition of the stones revealed that the majority (85%) consisted of calcium oxalate. The highest risk of recurrence and the need for multiple shockwave lithotripsy (SWL) sessions or surgical intervention appeared to be related with the presence of whewellite stones, which are the most challenging stones in childhood.
According the study results, the urinary stone types vary across different regions in our country, and the frequency of uric acid stones decreased going westward, while the frequency of oxalate stones increased. We conclude that this difference in the frequency of the type of urinary stones might reflect the regional dietary habits. Regional frequency and etiology studies for the types of urolithiasis may facilitate the approach to the treatment of urolithiasis.
小儿尿石症在全球范围内呈增长趋势。尿路结石的成分和发生率不仅在不同国家有所不同,在一个国家的不同地区也存在差异。因此,我们旨在确定我们所在地区(土耳其安纳托利亚西部内陆)儿童尿路结石的类型和发生率,并将我们的研究结果与我国其他地区的结果进行比较。
对2009年至2019年在我院接受治疗的53例小儿尿石症病例进行回顾性分析,评估其人口统计学数据、临床病程、放射学和代谢学检查结果、复发率以及结石成分。
患者的平均年龄为5.9±4.6(0.5 - 18)岁,其中女孩30例(56.6%),男孩23例(43.4%)。结石成分分析显示,大多数(85%)为草酸钙结石。复发风险最高以及需要多次冲击波碎石术(SWL)或手术干预的情况似乎与水草酸钙结石的存在有关,水草酸钙结石是儿童期最具挑战性的结石。
根据研究结果,我国不同地区的尿路结石类型各不相同,尿酸结石的发生率向西逐渐降低,而草酸钙结石的发生率则逐渐升高。我们得出结论,尿路结石类型发生率的这种差异可能反映了地区饮食习惯。针对尿石症类型的地区发生率和病因学研究可能有助于尿石症的治疗。