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精神分裂症、双相情感障碍和重度抑郁症患者的情绪-行为分离。

Emotion-behavior decoupling in individuals with schizophrenia, bipolar disorder, and major depressive disorder.

机构信息

Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences.

Mental Health Centre of Weifang city.

出版信息

J Abnorm Psychol. 2020 May;129(4):331-342. doi: 10.1037/abn0000499. Epub 2020 Jan 13.

Abstract

Failure in translating emotional salience into effortful behavior is thought to be a core feature of anhedonia and avolition in individuals with schizophrenia (SCZ), but little is known about emotion-behavior coupling in individuals with bipolar disorder (BD) and major depressive disorder (MDD). In this study, we compared emotion-behavior correspondence in participants with SCZ, BD, and MDD. Forty-two participants with SCZ, 44 participants with MDD, 43 participants with BD, and 43 healthy controls were recruited. A computerized anticipatory and consummatory pleasure task was used to evaluate emotion-behavior correspondence. Clinical ratings of negative symptoms and self-report anhedonia questionnaires were also administered. We found that participants with SCZ, MDD, and BD exhibited different levels of negative symptoms and self-reported anhedonia, as well as emotion-behavior decoupling. In SCZ participants, both desirable and undesirable images elicited lower correspondence between self-reported liking and behavior. In MDD and BD participants, undesirable images elicited lower emotion-behavior correspondence under both direct stimulus presentation and representation conditions, whereas deficits in emotion-behavior coupling under desirable conditions were only observed when stimuli were present. Taken together, emotion-behavior decoupling showed both common and unique patterns in participants with SCZ, MDD, and BD, and showed some associations with negative symptoms and anhedonia across the combined clinical sample. This finding may be helpful for early identification and the development of novel interventions for different psychiatric diagnoses. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

摘要

将情绪显著度转化为努力行为的失败被认为是精神分裂症(SCZ)个体快感缺失和意志缺失的核心特征,但人们对双相情感障碍(BD)和重性抑郁障碍(MDD)个体的情绪-行为耦合知之甚少。在这项研究中,我们比较了 SCZ、BD 和 MDD 个体的情绪-行为对应关系。招募了 42 名 SCZ 患者、44 名 MDD 患者、43 名 BD 患者和 43 名健康对照者。使用计算机化的预期和完成性愉悦任务来评估情绪-行为对应关系。还进行了阴性症状的临床评分和自我报告快感缺失问卷的评估。我们发现,SCZ、MDD 和 BD 患者表现出不同程度的阴性症状和自我报告的快感缺失,以及情绪-行为解耦。在 SCZ 患者中,令人愉快和不愉快的图像都引起自我报告的喜欢和行为之间的较低对应。在 MDD 和 BD 患者中,无论是直接呈现刺激还是代表条件,不愉快的图像都引起较低的情绪-行为对应,但仅在存在刺激时才观察到令人愉快的条件下情绪-行为耦合的缺陷。总的来说,情绪-行为解耦在 SCZ、MDD 和 BD 患者中表现出共同和独特的模式,并与整个临床样本中的阴性症状和快感缺失存在一定的关联。这一发现可能有助于对不同精神诊断进行早期识别和开发新的干预措施。(PsycInfo 数据库记录(c)2020 APA,保留所有权利)。

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