Nigam P K, Singh P K, Singh G, Kumar M
Department of Dermatology, Institute of Medical Sciences, B.H.U., Varanasi.
Indian J Lepr. 1988 Apr;60(2):303-5.
A case of uterine bleeding after intake of rifampicin is reported in a 35-year-old female. Provocation test was also positive. The underlying mechanism whether it was a hypersensitivity phenomenon like fixed drug eruption or due to induction of uterine acyl-hydrolase enzyme, is not clear. Uterine bleeding has not been observed as a side-effect of rifampicin in the past.
据报道，一名35岁女性在服用利福平后出现子宫出血。激发试验也呈阳性。其潜在机制尚不清楚，是像固定性药疹这样的超敏反应现象，还是由于子宫酰基水解酶的诱导。过去未观察到子宫出血是利福平的副作用。
