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在接受腹腔镜减重手术的患者中,添加腹横肌平面阻滞与增强恢复方案联合应用对阿片类药物消耗、术后止吐药使用和出院时间的影响:一项回顾性研究。

Association of the addition of a transversus abdominis plane block to an enhanced recovery program with opioid consumption, postoperative antiemetic use, and discharge time in patients undergoing laparoscopic bariatric surgery: a retrospective study.

机构信息

Anesthesiology, Rush University, Chicago, Illinois, USA

Anesthesiology, Rush University, Chicago, Illinois, USA.

出版信息

Reg Anesth Pain Med. 2020 Mar;45(3):180-186. doi: 10.1136/rapm-2019-101009. Epub 2020 Jan 12.

Abstract

BACKGROUND

Increasing numbers of laparoscopic bariatric surgeries are being performed and enhanced recovery from anesthesia and surgery (ERAS) protocols have been implemented to optimize care for these patients. We evaluated the effects of an anesthesiologist placed preoperative transversus abdominis plane block (TAP) as part of a bariatric surgery ERAS protocol. We hypothesized that an anesthesiologist placed preoperative TAP added to an ERAS protocol following laparoscopic bariatric surgery would reduce total opioid consumption.

METHODS

A retrospective cohort of consecutive patients between January 1, 2017 and December 31, 2018 at a single large tertiary care center studied. TAP blocks were added to the ERAS protocol beginning in the second quarter of 2017. The primary outcome was total opioid analgesia use in mg oral morphine equivalents. Secondary outcomes were antiemetics administered and length of hospitalization. Data were analyzed using a generalized linear mixed model adjusted for sociodemographic, surgical, and preoperative risk factors that have been associated with opioid and antiemetic use and length of hospitalization.

RESULTS

Five hundred and nine cases were analyzed; TAP blocks were performed in 94/144 (65%) laparoscopic Roux-en-Y gastric bypass (LRYGB) and in 172/365 (47%) laparoscopic sleeve gastrectomy (LSG) patients. Mean (95% CI) adjusted total opioid administered was lower by 11% (1% to 19%, p=0.02), antiemetic drug administration was lower by 15% (-2% to 25%, p=0.06) and discharge time lower by 39% (26% to 48%, p<0.01) following LRYGB in the TAP group. Mean (95% CI) adjusted total opioid administered was lower by 9% (2% to 16%, p<0.01), antiemetic drug administration was lower by 11% (3% to 18%, p0.01) and discharge time lower by 11% (2% to 18%, p=0.02) following LSG in the TAP group.

CONCLUSIONS

TAP blocks added to a laparoscopic bariatric surgery ERAS protocol were associated with decreased total opioid use, number of antiemetic treatments, and length of stay; however, these changes were not likely clinically important. Our findings do not support widespread clinical benefit of TAP use in ERAS protocols for laparoscopic bariatric surgery.

摘要

背景

越来越多的腹腔镜减重手术正在进行,并且已经实施了加速康复从麻醉和手术(ERAS)方案,以优化这些患者的护理。我们评估了麻醉师放置术前腹横肌平面阻滞(TAP)作为减重手术 ERAS 方案的一部分的效果。我们假设,在腹腔镜减重手术后,麻醉师放置的术前 TAP 与 ERAS 方案一起使用,将减少总阿片类药物的消耗。

方法

对 2017 年 1 月 1 日至 2018 年 12 月 31 日在一家大型三级保健中心进行的连续患者的回顾性队列进行了研究。从 2017 年第二季度开始,TAP 阻滞被添加到 ERAS 方案中。主要结局是口服吗啡等效物的总阿片类镇痛药用量。次要结局是给予止吐药和住院时间。使用广义线性混合模型分析数据,该模型调整了与阿片类药物和止吐药使用以及住院时间相关的社会人口统计学、手术和术前危险因素。

结果

分析了 509 例病例;在 144 例腹腔镜 Roux-en-Y 胃旁路术(LRYGB)和 365 例腹腔镜袖状胃切除术(LSG)患者中,TAP 阻滞分别进行了 94/144(65%)和 172/365(47%)。LRYGB 患者 TAP 组调整后的总阿片类药物用量降低 11%(1%至 19%,p=0.02),止吐药物的使用降低 15%(-2%至 25%,p=0.06),出院时间降低 39%(26%至 48%,p<0.01)。在 TAP 组中,LSG 患者调整后的总阿片类药物用量降低 9%(2%至 16%,p<0.01),止吐药物的使用降低 11%(3%至 18%,p<0.01),出院时间降低 11%(2%至 18%,p=0.02)。

结论

在腹腔镜减重手术 ERAS 方案中添加 TAP 阻滞与总阿片类药物用量减少、止吐药治疗次数减少和住院时间缩短有关;然而,这些变化可能没有临床意义。我们的研究结果不支持 TAP 在腹腔镜减重手术 ERAS 方案中广泛应用的临床益处。

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