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腹腔镜辅助与超声引导腹横肌平面阻滞在腹腔镜减重手术中的比较:一项随机对照试验。

Laparoscopic assisted versus ultrasound guided transversus abdominis plane block in laparoscopic bariatric surgery: a randomized controlled trial.

机构信息

Anesthesiology, Surgical Intensive Care and Pain Medicine Department, Faculty of Medicine, Kafr ElSheikh University, Kafr ElSheikh, 33516, Egypt.

Surgery Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

出版信息

BMC Anesthesiol. 2024 Apr 6;24(1):133. doi: 10.1186/s12871-024-02498-6.

Abstract

BACKGROUND

Transversus abdominis plane block (TAPB) guided by laparoscopy and ultrasound showed promise in enhancing the multimodal analgesic approach following several abdominal procedures. This study aimed to compare the efficacy and safety between Laparoscopic (LAP) TAP block (LTAP) and ultrasound-guided TAP block (UTAP) block in patients undergoing LAP bariatric surgery.

PATIENTS AND METHODS

This non-inferiority randomized controlled single-blind study was conducted on 120 patients with obesity scheduled for LAP bariatric surgeries. Patients were allocated into two equal groups: LTAP and UTAP, administered with 20 mL of 0.25% bupivacaine on each side.

RESULTS

There was no statistically significant difference in the total morphine consumption, Visual Analogue Scale (VAS) score at all times of measurements, and time to the first rescue analgesia (p > .05) between both groups. The duration of anesthesia and duration of block performance were significantly shorter in the LTAP group than in the UTAP group (p < .001). Both groups had comparable post-operative heart rate, mean arterial pressure, adverse effects, and patient satisfaction.

CONCLUSIONS

In LAP bariatric surgery, the analgesic effect of LTAP is non-inferior to UTAP, as evidenced by comparable time to first rescue analgesia and total morphine consumption with similar safety blocking through the low incidence of post-operative complications and patient satisfaction.

TRIAL REGISTRATION

The study was registered in Pan African Clinical Trials Registry (PACTR) (ID: PACTR202206871825386) on June 29, 2022.

摘要

背景

腹腔镜和超声引导下的腹横肌平面阻滞(TAPB)在多种腹部手术后增强多模式镇痛方法方面显示出前景。本研究旨在比较腹腔镜(LAP)TAP 阻滞(LTAP)和超声引导 TAP 阻滞(UTAP)在接受 LAP 减肥手术患者中的疗效和安全性。

患者和方法

这是一项非劣效性随机对照单盲研究,纳入了 120 名计划接受 LAP 减肥手术的肥胖患者。患者被随机分为两组:LTAP 和 UTAP 组,在每侧注射 20 mL 0.25%布比卡因。

结果

两组患者的总吗啡消耗量、所有时间点的视觉模拟评分(VAS)以及首次解救镇痛时间均无统计学差异(p>0.05)。LTAP 组的麻醉持续时间和阻滞持续时间明显短于 UTAP 组(p<0.001)。两组患者的术后心率、平均动脉压、不良反应和患者满意度均无差异。

结论

在 LAP 减肥手术中,LTAP 的镇痛效果与 UTAP 相当,表现在首次解救镇痛时间和总吗啡消耗量相似,且通过术后并发症发生率和患者满意度低来实现类似的安全阻滞。

试验注册

该研究于 2022 年 6 月 29 日在泛非临床试验注册中心(PACTR)(ID:PACTR202206871825386)注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f75/10998407/94af4c850f17/12871_2024_2498_Fig1_HTML.jpg

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