• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

经动脉放射性栓塞术中基于γ相机法的肝肺分流估计软件开发

Software development for hepatopulmonary shunt estimation by gamma camera method in transarterial radioembolization.

作者信息

Jha Ashish Kumar, Mithun Sneha, Puranik Ameya, Purandare Nilendu C, Shah Sneha, Agrawal Archi, Kulkarni Suyash S, Shetty Nitin, Rangarajan Venkatesh

机构信息

Department of Nuclear Medicine and Molecular Imaging, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Department of Raiodiagnosis, Tata Memorial Hospital, Mumbai, Maharashtra, India.

出版信息

World J Nucl Med. 2019 Dec 18;18(4):366-372. doi: 10.4103/wjnm.WJNM_115_18. eCollection 2019 Oct-Dec.

DOI:10.4103/wjnm.WJNM_115_18
PMID:31933552
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6945361/
Abstract

Trans-arterial radioembolization (TARE) is an established treatment for inoperable hepatocellular carcinoma and liver metastases from Carcinoma of gastrointestinal tract. Radiation-induced toxicity to the lung parenchyma is the dose-limiting factor in TARE. Pretreatment hepatopulmonary shunt (HPS) is estimated by gamma camera method by transarterial administration of 370MBq Tc macro aggregated albumin. We have developed HPS software on XELERIS-1.123 workstation, GE medical systems, Milwaukee, USA, for accurate calculation of HPS. This software has also been tested on a higher version of XELERIS workstation, and it has been found to work well in all versions.

摘要

经动脉放射性栓塞术（TARE）是一种用于无法手术切除的肝细胞癌和胃肠道癌肝转移的既定治疗方法。辐射对肺实质的毒性是TARE中的剂量限制因素。通过经动脉注射370MBq锝标记的大聚合白蛋白，利用γ相机法估算治疗前的肝肺分流（HPS）。我们在美国密尔沃基的通用电气医疗系统公司的XELERIS-1.123工作站上开发了HPS软件，用于准确计算HPS。该软件也已在更高版本的XELERIS工作站上进行了测试，并且发现在所有版本中都能正常运行。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1aca/6945361/212fc2f1f985/WJNM-18-366-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1aca/6945361/ff359c862de7/WJNM-18-366-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1aca/6945361/e7ffd94cfbbf/WJNM-18-366-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1aca/6945361/697cfb05efbc/WJNM-18-366-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1aca/6945361/212fc2f1f985/WJNM-18-366-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1aca/6945361/ff359c862de7/WJNM-18-366-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1aca/6945361/e7ffd94cfbbf/WJNM-18-366-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1aca/6945361/697cfb05efbc/WJNM-18-366-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1aca/6945361/212fc2f1f985/WJNM-18-366-g006.jpg

相似文献

1
Software development for hepatopulmonary shunt estimation by gamma camera method in transarterial radioembolization.经动脉放射性栓塞术中基于γ相机法的肝肺分流估计软件开发
World J Nucl Med. 2019 Dec 18;18(4):366-372. doi: 10.4103/wjnm.WJNM_115_18. eCollection 2019 Oct-Dec.
2
The value of Tc-MAA SPECT/CT for lung shunt estimation in Y radioembolization: a phantom and patient study.锝-99m标记的大颗粒聚合白蛋白单光子发射计算机断层扫描/计算机断层扫描在钇-90放射性栓塞中评估肺分流的价值：模型与患者研究
EJNMMI Res. 2018 Jun 15;8(1):50. doi: 10.1186/s13550-018-0402-8.
3
Portal vein embolization for closure of marked arterioportal shunt of hepatocellular carcinoma to enable radioembolization: A case report.门静脉栓塞术用于闭合肝细胞癌明显的动门脉分流以实现放射性栓塞：一例报告。
World J Gastrointest Surg. 2023 Dec 27;15(12):2926-2931. doi: 10.4240/wjgs.v15.i12.2926.
4
Hepatopulmonary shunting in patients with primary and secondary liver tumors scheduled for radioembolization.计划接受放射性栓塞治疗的原发性和继发性肝肿瘤患者的肝肺分流。
Eur J Radiol. 2015 Feb;84(2):201-7. doi: 10.1016/j.ejrad.2014.11.004. Epub 2014 Nov 13.
5
Comparative analysis of hepatopulmonary shunt obtained from pretherapy 99mTc MAA scintigraphy and post-therapy 90Y Bremsstrahlung imaging in 90Y microsphere therapy.90Y微球治疗中，治疗前99mTc MAA闪烁显像与治疗后90Y轫致辐射显像所获肝肺分流的对比分析。
Nucl Med Commun. 2012 May;33(5):486-90. doi: 10.1097/MNM.0b013e328351672d.
6
A simple method for estimating dose delivered to hepatocellular carcinoma after yttrium-90 glass-based radioembolization therapy: preliminary results of a proof of concept study.一种估算钇-90玻璃基放射性栓塞治疗后肝细胞癌所接受剂量的简单方法：概念验证研究的初步结果
J Vasc Interv Radiol. 2014 Feb;25(2):277-87. doi: 10.1016/j.jvir.2013.11.007.
7
Tc-99m-MAA lung shunt fraction before Y-90 radioembolization is low among patients with non-hepatocellular carcinoma malignancies.在非肝细胞癌恶性肿瘤患者中，钇-90放射性栓塞术前的锝-99m-大颗粒聚合白蛋白肺分流分数较低。
Nucl Med Commun. 2019 Nov;40(11):1154-1157. doi: 10.1097/MNM.0000000000001089.
8
Y radioembolization dosimetry using a simple semi-quantitative method in intrahepatic cholangiocarcinoma: Glass versus resin microspheres.使用一种简单的半定量方法进行 Y 放射性栓塞治疗肝内胆管细胞癌的放射性活度分布：玻璃微球与树脂微球的比较。
Nucl Med Biol. 2018 Apr;59:22-28. doi: 10.1016/j.nucmedbio.2018.01.001. Epub 2018 Jan 16.
9
Hepatopulmonary shunting after surgical, interventional and systemic therapy in patients with liver malignancies scheduled for radioembolization.计划接受放射性栓塞治疗的肝脏恶性肿瘤患者在手术、介入和全身治疗后的肝肺分流。
Acta Radiol. 2016 Aug;57(8):908-13. doi: 10.1177/0284185115605680. Epub 2015 Sep 23.
10
Impact of SPECT corrections on 3D-dosimetry for liver transarterial radioembolization using the patient relative calibration methodology.使用患者相对校准方法时，单光子发射计算机断层扫描（SPECT）校正对肝动脉放射性栓塞三维剂量测定的影响。
Med Phys. 2016 Jul;43(7):4053. doi: 10.1118/1.4953203.

引用本文的文献

1
Advancing Nuclear Medicine through Discovery, Invention, and Innovation - Contribution of a Physicist and Scientist (Vikram Sarabhai Memorial Oration-2023).通过发现、发明与创新推动核医学发展——一位物理学家和科学家的贡献（2023年维克拉姆·萨拉巴伊纪念演讲）
Indian J Nucl Med. 2024 Nov-Dec;39(6):421-427. doi: 10.4103/ijnm.ijnm_118_24. Epub 2025 Mar 20.

本文引用的文献

1
Is there a correlation between planar scintigraphy after 99mTc-MAA and 90Y administration?99mTc-MAA 平面闪烁显像与 90Y 给药之间是否存在相关性？
Nucl Med Commun. 2016 Feb;37(2):107-9. doi: 10.1097/MNM.0000000000000425.
2
Comparative analysis of hepatopulmonary shunt obtained from pretherapy 99mTc MAA scintigraphy and post-therapy 90Y Bremsstrahlung imaging in 90Y microsphere therapy.90Y微球治疗中，治疗前99mTc MAA闪烁显像与治疗后90Y轫致辐射显像所获肝肺分流的对比分析。
Nucl Med Commun. 2012 May;33(5):486-90. doi: 10.1097/MNM.0b013e328351672d.
3
Planning transarterial radioembolization of colorectal liver metastases with Yttrium 90 microspheres: evaluation of a sequential diagnostic approach using radiologic and nuclear medicine imaging techniques.
使用钇90微球进行结直肠癌肝转移的经动脉放射性栓塞治疗规划：采用放射学和核医学成像技术的序贯诊断方法评估
Eur Radiol. 2008 May;18(5):892-902. doi: 10.1007/s00330-007-0836-2. Epub 2008 Jan 4.
4
Recommendations for radioembolization of hepatic malignancies using yttrium-90 microsphere brachytherapy: a consensus panel report from the radioembolization brachytherapy oncology consortium.使用钇-90微球近距离放射治疗进行肝恶性肿瘤放射性栓塞治疗的建议：放射性栓塞近距离放射治疗肿瘤学联盟的共识小组报告
Int J Radiat Oncol Biol Phys. 2007 May 1;68(1):13-23. doi: 10.1016/j.ijrobp.2006.11.060.
5
Management and prevention of adverse effects related to treatment of liver tumours with 90Y microspheres.90Y微球治疗肝肿瘤相关不良反应的管理与预防
Nucl Med Commun. 2007 Jan;28(1):21-4. doi: 10.1097/MNM.0b013e3280121a8f.
6
Radioembolization with yttrium-90 microspheres: a state-of-the-art brachytherapy treatment for primary and secondary liver malignancies: part 3: comprehensive literature review and future direction.钇-90微球放射性栓塞：原发性和继发性肝脏恶性肿瘤的先进近距离放射治疗：第3部分：综合文献综述与未来方向
J Vasc Interv Radiol. 2006 Oct;17(10):1571-93. doi: 10.1097/01.RVI.0000236744.34720.73.
7
Treatment of unresectable hepatocellular carcinoma with use of 90Y microspheres (TheraSphere): safety, tumor response, and survival.使用90Y微球（TheraSphere）治疗不可切除肝细胞癌：安全性、肿瘤反应和生存率。
J Vasc Interv Radiol. 2005 Dec;16(12):1627-39. doi: 10.1097/01.RVI.0000184594.01661.81.
8
Yttrium-90 microsphere therapy for hepatic malignancy: devices, indications, technical considerations, and potential complications.钇-90微球治疗肝恶性肿瘤：装置、适应症、技术要点及潜在并发症
Radiographics. 2005 Oct;25 Suppl 1:S41-55. doi: 10.1148/rg.25si055515.
9
Treatment of unresectable hepatocellular carcinoma with intrahepatic yttrium 90 microspheres: factors associated with liver toxicities.肝内钇 90 微球治疗不可切除肝细胞癌：与肝毒性相关的因素
J Vasc Interv Radiol. 2005 Feb;16(2 Pt 1):205-13. doi: 10.1097/01.rvi.00001142592.89564.f9.
10
Radiation-induced ulceration of the stomach secondary to hepatic embolization with radioactive yttrium microspheres in the treatment of metastatic colon cancer.放射性钇微球肝动脉栓塞治疗转移性结肠癌继发的放射性胃溃疡。
J Gastroenterol Hepatol. 2004 Mar;19(3):347-9. doi: 10.1111/j.1440-1746.2003.03322.x.