Takagaki Masatoshi, Nakagawa Tomoyoshi, Kawabata Shuhei, Izutsu Nobuyuki, Nishida Takeo, Nakamura Hajime, Kishima Haruhiko
Department of Neurosurgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
NMC Case Rep J. 2019 Dec 18;7(1):35-38. doi: 10.2176/nmccrj.cr.2019-0097. eCollection 2020 Jan.
The number of heart transplantations performed in Japan has been continuously increasing. Here, we report the case of a patient with an unruptured cerebral artery aneurysm after undergoing heart transplantation and was treated using coil embolization. The patient was a 50-year-old woman who was positive for heparin-induced thrombocytopenia (HIT) antibodies and underwent heart transplantation for dilated cardiomyopathy. An unruptured middle cerebral artery aneurysm was treated with coil embolization using argatroban as a heparin substitute. The patient was discharged without any complications. Despite these patients with heart transplantation are characterized by high HIT antibodies rate and the need for immunosuppressive agents, they currently have an excellent prognosis, especially in Japan. Therefore, the knowledge of patient characteristics after heart transplantation is essential for ensuring that these patients receive the most appropriate treatment.
日本进行心脏移植的数量一直在持续增加。在此，我们报告一例心脏移植术后未破裂脑动脉瘤患者，该患者接受了弹簧圈栓塞治疗。患者为一名50岁女性，肝素诱导的血小板减少症（HIT）抗体呈阳性，因扩张型心肌病接受心脏移植。使用阿加曲班作为肝素替代品，通过弹簧圈栓塞治疗未破裂的大脑中动脉瘤。患者无任何并发症出院。尽管这些心脏移植患者的特点是HIT抗体率高且需要免疫抑制剂，但目前他们的预后良好，尤其是在日本。因此，了解心脏移植后患者的特征对于确保这些患者接受最合适的治疗至关重要。
