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面神经和鼓索神经鞘瘤:病例系列,以及在后增强 3D-T1 Turbo 场回波和 CT 图像(TURFECT)的非刚性配准在其诊断和手术治疗中的优势。

Facial nerve and chorda tympani schwannomas: Case series, and advantages of using non-rigid registration of post-enhanced 3D-T1 Turbo Field Echo and CT images (TURFECT) in their diagnosis and surgical treatment.

机构信息

Department of Otolaryngology, Head and Neck Surgery, Yamagata University Faculty of Medicine, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan.

Otorhinolaryngology-Head and Neck Surgery Department, University Hospital of Verona, Italy.

出版信息

Auris Nasus Larynx. 2020 Jun;47(3):383-390. doi: 10.1016/j.anl.2019.12.006. Epub 2020 Jan 13.

DOI:10.1016/j.anl.2019.12.006
PMID:31948824
Abstract

OBJECTIVE

Facial nerve schwannomas (FNSs) and chorda tympani schwannomas are very rare. Diagnosis of these tumors is sometimes difficult, and treatment consensus has not yet been reached. We report here a series of cases of FNS and chorda tympani schwannoma and highlight the usefulness of our newly developed technique of non-rigid registration of post-enhanced 3D-T1 Turbo Field Echo and CT images (TURFECT) in their diagnosis and treatment.

METHODS

MRI images were adjusted with the corresponding CT images in terms of angle and position in order to index the anatomical structures. The well-enhanced T1-Gd+ lesions of tumors having good blood flow show up as bright red after color mapping.

RESULTS

Between 2014 and 2018, five patients were diagnosed with schwannomas in the temporal bone: three with FNS and two with chorda tympani schwannoma. Gd-enhanced MRI showed only a high-intensity mass, and we could not detect the relationship between tumor-like mass and bone (including the ossicles) by MRI only. In contrast, TURFECT was very useful for diagnosing the precise location, allowing us to decide on an endoscopic surgical plan in some of our cases. An endoscope enabled visualization of the medial wall of the tympanic cavity and the status of the tumors, thus we could successfully perform transcanal endoscopic biopsy and resections.

CONCLUSION

TURFECT can be very useful for diagnosis of FNSs and chorda tympani schwannomas and for deciding surgical treatments such as a transcanal endoscopic approach.

摘要

目的

面神经鞘瘤(FNS)和鼓索神经鞘瘤非常罕见。这些肿瘤的诊断有时较为困难,尚未达成治疗共识。我们在此报告一系列 FNS 和鼓索神经鞘瘤病例,并强调我们新开发的非刚性增强后 3D-T1 涡轮场回波和 CT 图像(TURFECT)配准技术在其诊断和治疗中的作用。

方法

根据角度和位置调整 MRI 图像和相应的 CT 图像,以标记解剖结构。具有良好血流的肿瘤的增强 T1-Gd+病变在彩色映射后呈现鲜艳的红色。

结果

2014 年至 2018 年间,5 名患者被诊断为颞骨神经鞘瘤:3 例为 FNS,2 例为鼓索神经鞘瘤。钆增强 MRI 仅显示高强度肿块,我们仅通过 MRI 无法检测到肿瘤样肿块与骨(包括听小骨)之间的关系。相比之下,TURFECT 对于诊断精确位置非常有用,使我们能够在某些病例中决定内镜手术方案。内镜可使我们观察到鼓室内侧壁和肿瘤的状态,从而成功地进行了经耳道内镜活检和切除术。

结论

TURFECT 对于 FNS 和鼓索神经鞘瘤的诊断以及决定经耳道内镜等手术治疗非常有用。

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