Facile synthesis of copper ferrite nanoparticles with chitosan composite for high-performance electrochemical sensor.

Herein, the synthesis of copper ferrite nanoparticles (CuFeO NPs)/chitosan have been prepared by sonochemical route under ultrasonic irradiation bath at 40 kHz and 50 W. A high sensitive and stable modified electrochemical sensor was developed using a composition of copper ferrite nanoparticles coordinated with biopolymer through a facile ultrasound approach. Besides, power and frequency parameters are highly important for sonochemical synthesis and specifically structure, and size of the nanomaterials development during the ultrasonic irradiation time. In this work, ultrasonic bath was used to synthesis of CuFeO nanomaterial at 40 kHz with 1 h. CuFeO/chitosan was characterized by FESEM, EDX, XRD and electrochemical methods. Furthermore, 8-hydroxyguanine is one of biomarker by oxidative stress. The concentrations of 8-hydroxyguanine within a cell are a measurement of oxidative stress in human body. Consequently, the measurement of 8-hydroxyguanine in blood serum samples with high specificity is of greatest importance. The CuFeO/chitosan modified electrode is displayed a low detection limit of 8.6 nM and long linear range (0.025-697.175 µM).