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马的三维超高密度心脏电解剖标测:方法学

Three dimensional ultra-high-density electro-anatomical cardiac mapping in horses: methodology.

作者信息

Van Steenkiste Glenn, De Clercq Dominique, Boussy Tim, Vera Lisse, Schauvliege Stijn, Decloedt Annelies, van Loon Gunther

机构信息

Department of Large Animal Internal Medicine, Equine Cardioteam, Ghent University, Ghent, Belgium.

Department of Cardiology, AZ Groeninge, Kortrijk, Belgium.

出版信息

Equine Vet J. 2020 Sep;52(5):765-772. doi: 10.1111/evj.13229. Epub 2020 Feb 19.

Abstract

BACKGROUND

Ultra-high-density cardiac mapping allows very accurate characterisation of atrial and ventricular electrophysiology and activation timing.

OBJECTIVE

To describe the technique and evaluate the feasibility of magnetic electro-anatomical mapping of the equine heart.

STUDY DESIGN

In vivo experimental method development.

METHODS

A mapping system using an 8.5F bidirectional deflectable catheter with a deployable mini-basket (3-22 mm) containing 64 electrodes divided over eight splines was evaluated. Based upon predefined beat acceptance criteria, the system automatically acquires endocardial electrograms and catheter location information. Electro-anatomical maps were acquired from four horses in sinus rhythm under general anaesthesia.

RESULTS

All endocardial areas within each chamber could be reached. Access to the left atrium required the use of a deflectable sheath. With the exception of the left atrial map of horse 1, all four chambers in all four horses could be mapped. Optimisation of the beat acceptance criteria led to a reduction in manual correction of the automatically accepted beats from 13.1% in the first horse to 0.4% of the beats in the last horse.

MAIN LIMITATIONS

Only a limited number of horses were included in the study.

CONCLUSION

Ultra-high-density 3D electro-anatomical mapping is feasible in adult horses and is a promising tool for electrophysiological research and characterisation of complex arrhythmias.

摘要

背景

超高密度心脏标测能够非常准确地表征心房和心室的电生理学及激动时间。

目的

描述马心脏磁电解剖标测技术并评估其可行性。

研究设计

体内实验方法开发。

方法

评估一种标测系统,该系统使用带有可展开微型篮(3 - 22毫米)的8.5F双向可弯导管,微型篮包含分布在八个样条上的64个电极。基于预定义的搏动接受标准,该系统自动采集心内膜电图和导管位置信息。在全身麻醉下,从四匹窦性心律的马获取电解剖图。

结果

每个心腔内的所有心内膜区域均可到达。进入左心房需要使用可弯鞘管。除马1的左心房图外,所有四匹马的四个心腔均可进行标测。搏动接受标准的优化使自动接受搏动的人工校正从第一匹马的13.1%降至最后一匹马的0.4%。

主要局限性

本研究仅纳入了有限数量的马匹。

结论

超高密度三维电解剖标测在成年马中是可行的,并且是用于电生理研究和复杂心律失常表征的有前景的工具。

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