Vonk Patty E, Rotteveel Perry J, Ravesloot Madeline J L, Ho Jean-Pierre T F, de Lange Jan, de Vries Nico
Department of Otorhinolaryngology - Head and Neck Surgery, OLVG, Amsterdam, the Netherlands.
Department of Otorhinolaryngology, Medical Centre Jan van Goyen, Amsterdam, the Netherlands.
J Clin Sleep Med. 2020 Jan 15;16(1):73-80. doi: 10.5664/jcsm.8126. Epub 2019 Nov 27.
(1) To evaluate surgical success in patients with obstructive sleep apnea undergoing maxillomandibular advancement (MMA) stratifying for the reduction of both the total apnea-hypopnea index (AHI) and the AHI in the supine and nonsupine position; (2) to evaluate the influence of position dependency on surgical outcome; and (3) to analyze the prevalence of residual position-dependent obstructive sleep apnea (OSA) in nonresponders after MMA.
A single-center retrospective study including a consecutive series of patients with OSA undergoing MMA between August 2011 and February 2019.
In total, 57 patients were included. The overall surgical success was 52.6%. No significant difference in surgical success between nonpositional patients (NPP) and positional patients (PP) with OSA was found. Surgical success of the supine AHI was not significantly different between NPP and PP, but surgical success of the nonsupine AHI was significantly greater in NPP than in PP. Of the 17 preoperative NPP, 13 of them moved to being PP with less severe OSA postoperatively. In total, 21 out of 27 nonresponders (77.8%) were PP postoperatively.
No significant difference in surgical success between NPP and PP undergoing MMA was found. However, the improvement of total and nonsupine AHI in NPP was significantly greater compared to PP. In nonresponders, a postoperative shift from severe OSA in NPP to less severe OSA in PP was found, caused by a greater reduction of the nonsupine AHI than the supine AHI postoperatively. In patients with residual OSA in the supine position after MMA, additional treatment with positional therapy can be indicated.
(1)评估接受颌骨前徙术(MMA)的阻塞性睡眠呼吸暂停患者的手术成功率,根据仰卧位和非仰卧位总呼吸暂停低通气指数(AHI)的降低情况进行分层;(2)评估体位依赖性对手术结果的影响;(3)分析MMA术后无反应者中残留体位依赖性阻塞性睡眠呼吸暂停(OSA)的患病率。
一项单中心回顾性研究,纳入2011年8月至2019年2月期间连续接受MMA治疗的OSA患者系列。
共纳入57例患者。总体手术成功率为52.6%。未发现阻塞性睡眠呼吸暂停非体位性患者(NPP)和体位性患者(PP)之间的手术成功率有显著差异。仰卧位AHI的手术成功率在NPP和PP之间无显著差异,但非仰卧位AHI的手术成功率在NPP中显著高于PP。17例术前NPP患者中,13例术后转变为PP,OSA症状减轻。27例无反应者中,共有21例(77.8%)术后为PP。
接受MMA的NPP和PP之间的手术成功率无显著差异。然而,与PP相比,NPP中总AHI和非仰卧位AHI的改善显著更大。在无反应者中,发现术后从NPP中的重度OSA转变为PP中的轻度OSA,这是由于术后非仰卧位AHI的降低幅度大于仰卧位AHI。对于MMA术后仰卧位仍有残留OSA的患者,可考虑采用体位治疗进行额外治疗。