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Synthesis and Antibacterial Activity of Polymerizable Acryloyloxyalkyltriethyl Ammonium Salts.

作者信息

Mancuso Raffaella, Amuso Roberta, Armentano Biagio, Grasso Giuseppe, Rago Vittoria, Cappello Anna Rita, Galiano Francesco, Figoli Alberto, De Luca Giorgio, Hoinkis Jan, Gabriele Bartolo

机构信息

Department of Chemistry and Chemical Technologies, University of Calabria, Via P. Bucci, 12/C, 87036, Arcavacata di Rende, CS, Italy.

Department of Pharmacy and Health and Nutritional Sciences, University of Calabria, 87036, Arcavacata di Rende, CS, Italy.

出版信息

Chempluschem. 2017 Oct;82(10):1233-1234. doi: 10.1002/cplu.201700329. Epub 2017 Aug 9.

DOI:10.1002/cplu.201700329
PMID:31957992
Abstract

Invited for this month's cover are the collaborating groups at the University of Calabria (Unical, Italy)-Department of Chemistry and Chemical Technologies (CTC) and Department of Pharmacy and Health and Nutritional Sciences (PHNS), at the National Research Council (CNR, Italy), Institute on Membrane Technology (ITM), and at the Karlsruhe University of Applied Sciences (HSKA, Germany), Institute of Applied Research (IAR), which cooperated in the framework of the European Union's Horizon 2020 project "VicInAqua". The front cover shows the structure of an acryloxyalkyltrithylammonium (AATEA) cation, characterized by a polymerizable end, a long-chain alkyl linker, and a quaternary ammonium moiety. The bromide salts (AATEABs) have been synthesized by a two-step procedure carried out entirely under air without any need for chromatographic purifications. Some AATEABs have shown significant antimicrobial activity and represent useful precursors for the preparation of polymeric films with antimicrobial properties. Read the full text of the article at 10.1002/cplu.201700194.

摘要

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