Department of Urology, Lenox Hill Hospital, Zucker School of Medicine at Hofstra/Northwell, New York, NY, 10075, USA.
Department of Surgery and Urology, Miami Transplant Institute, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, FL, 33136, USA.
Curr Urol Rep. 2020 Jan 18;21(1):1. doi: 10.1007/s11934-020-0953-x.
Kidney transplantation and gender affirmation treatments are becoming increasingly more prevalent due to advances in technology. However, there is a paucity of data regarding kidney transplantation in transgender patients. Interesting considerations must be made in this patient population, since there are many hormonal interactions with kidney function and the transplantation process.
The diagnosis of estimated glomerular filtration rate (eGFR), preoperative assessment/counseling, decreased testosterone levels in a transgender male to female patient, increased estrogen/progesterone in a female to male patient, and drug side effects all have important and unique implications for kidney transplant recipients. Kidney transplantation can be safely and effectively managed in transgender patients with special considerations in eGFR calculations, mental health/lifestyle counseling, and drug interactions.
随着技术的进步，肾移植和性别肯定治疗越来越普遍。然而，关于跨性别患者的肾移植数据很少。由于肾脏功能和移植过程中有许多激素相互作用，因此必须对这一患者群体进行有趣的考虑。
估算肾小球滤过率（eGFR）的诊断、术前评估/咨询、跨性别男性到女性患者的睾酮水平降低、女性到男性患者的雌二醇/孕酮增加，以及药物副作用，所有这些对肾移植受者都有重要的、独特的影响。肾移植可以在跨性别患者中安全有效地进行，在 eGFR 计算、心理健康/生活方式咨询和药物相互作用方面需要特别考虑。
