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颈椎间盘置换术后6年的椎体骨质溶解

Vertebral Body Osteolysis 6 Years After Cervical Disk Arthroplasty.

作者信息

Harati Ali, Oni Paul, Oles Lucas, Reuter Thomas, Hamdan Mohammad

机构信息

Klinik für Neurochirurgie, Klinikum Dortmund GmbH, Dortmund, Germany.

Department of Neurosurgery, Mediapark Klinik, Cologne, NRW, Germany.

出版信息

J Neurol Surg A Cent Eur Neurosurg. 2020 Mar;81(2):188-192. doi: 10.1055/s-0039-1698435. Epub 2020 Jan 21.

DOI:10.1055/s-0039-1698435
PMID:31962353
Abstract

Cervical arthroplasty is an accepted and widely performed surgical intervention with usually favorable outcomes. We report a rare case of a 37-year-old woman who presented with vertebral body osteolysis, 6 years after two-level cervical arthroplasty (C5-C6 and C6-C7). The patient showed no initial complications, but at year 6 she presented with neck and radicular arm pain. Diagnostic imaging revealed osteolysis of the vertebral body C6. The patient subsequently underwent removal of the two prostheses and C6 corpectomy, followed by bridging C5 to C7 and anterior fixation. During surgery, the mantle of the prostheses appeared broken, with the core expulsed anteriorly and embedded in granulomatous scar tissue. Pathologic evaluation of the samples showed partially proliferating fibroblasts, giant cell reaction, and textile particles. Postoperatively, clinical symptoms resolved with no residual deficits. Additional research should be performed to assess the long-term complications of this procedure that should be included in the patient informed consent materials.

摘要

颈椎置换术是一种被广泛接受且实施广泛的外科手术干预,通常预后良好。我们报告了一例罕见病例,一名37岁女性在接受两节段颈椎置换术(C5-C6和C6-C7)6年后出现椎体骨质溶解。患者最初未出现并发症,但在第6年时出现颈部和神经根性手臂疼痛。诊断性影像学检查显示C6椎体骨质溶解。患者随后接受了两枚假体取出及C6椎体次全切除,接着进行了C5至C7的桥接和前路固定。手术过程中,假体的外壳出现破裂,核心向前排出并嵌入肉芽肿性瘢痕组织中。样本的病理评估显示有成纤维细胞部分增生、巨细胞反应和纺织颗粒。术后,临床症状得到缓解,无残留神经功能缺损。应开展更多研究以评估该手术的长期并发症,并将其纳入患者知情同意书中。

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Vertebral Body Osteolysis 6 Years After Cervical Disk Arthroplasty.颈椎间盘置换术后6年的椎体骨质溶解
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引用本文的文献

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Heterotopic ossification, osteolysis and implant failure following cervical total disc replacement with the M6-C™ artificial disc.颈椎全椎间盘置换术后 M6-C™人工椎间盘的异位骨化、骨溶解和假体失败。
Eur Spine J. 2024 Mar;33(3):1292-1299. doi: 10.1007/s00586-024-08129-5. Epub 2024 Feb 16.
2
The lexicon for periprosthetic bone loss versus osteolysis after cervical disc arthroplasty: a systematic review.颈椎间盘置换术后假体周围骨丢失与骨溶解的词汇:系统评价。
Eur Spine J. 2022 Apr;31(4):830-842. doi: 10.1007/s00586-021-07092-9. Epub 2022 Jan 9.